HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 25910212, 25416956, 16189514, 21516116, 29892012, 32296183, 35235311, 34349018, 31515488, unassigned1654, unassigned1304
Identification Methods two hybrid, cross-linking study, two hybrid prey pooling approach, two hybrid array, split luciferase complementation, two hybrid bait and prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0001738 - morphogenesis of a polarized epithelium
GO:0005200 - structural constituent of cytoskeleton
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
and 25 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 375
Hs

1 375
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Oc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024