HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005912 - adherens junction and 1 others more... GO:0030027 - lamellipodium
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 513
+	Hs
		891892 ACTB_HUMAN (1-375): 0: 603: 100.00		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		929923 ACTG_HUMAN (1-375): 0: 601: 98.93		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		932254 ACTC_HUMAN (2-375): 0: 592: 94.12		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		930026 ACTG_HUMAN (1-375): 0: 601: 98.93		ABI2_HUMAN (1-513): 1.82e-91: 290: 100.00
+	Hs
		1164359 POTEE_HUMAN (1-375): 0: 736: 92.00		Q96D37_HUMAN (276-513): 7.97e-32: 131: 17.86
+	Hs
		548727 POTEE_HUMAN (1-375): 0: 736: 92.00		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86
+	Hs
		548718 ACTBL_HUMAN (2-375): 0: 735: 91.71		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86
+	Hs
		891762 ACTB_HUMAN (1-375): 0: 603: 100.00		SRC8_HUMAN (271-507): 2.78e-32: 131: 17.84
+	Hs
		929863 ACTG_HUMAN (1-375): 0: 601: 98.93		SRC8_HUMAN (271-507): 2.78e-32: 131: 17.84
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 592: 94.12		SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92
+	Hs
		932154 ACTC_HUMAN (2-375): 0: 592: 94.12		SRC8_HUMAN (271-507): 2.78e-32: 131: 17.84
+	Hs
		548675 ACTA_HUMAN (2-375): 0: 591: 94.12		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86
+	Hs
		891671 ACTB_HUMAN (1-375): 0: 603: 100.00		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		924453 ACTG_HUMAN (1-375): 0: 601: 98.93		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		924456 ACTC_HUMAN (2-375): 0: 592: 94.12		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		924454 ACTH_HUMAN (2-375): 0: 589: 93.58		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93