Protein: TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) (PCAF-associated factor 65-alpha) (PAF65-alpha)

Gene: TAF6L
Organism: Homo sapiens
Interactions: 130
UniProt ID: Q9Y6J9

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000124 - SAGA complex
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1159351

TAF9
Transcription initiation factor TFIID subunit 9

9

8

Small-scale

0.975

High

1438409

TAF9B
Transcription initiation factor TFIID subunit 9B

6

8

High-throughput

0.954

High

1384799

TADA1
Transcriptional adapter 1

5

0

High-throughput

0.872

High

284999

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

3

7

High-throughput

0.861

High

1369236

KAT2B
Histone acetyltransferase KAT2B

6

10

Small-scale

0.733

High

1091658

TAF10
Transcription initiation factor TFIID subunit 10

6

5

Small-scale

0.730

High

1157618

TAF12
Transcription initiation factor TFIID subunit 12

5

5

High-throughput

0.716

High

283636

SUPT3
Transcription initiation protein SPT3 homolog

5

5

Small-scale

0.714

High

284907

TADA3
Transcriptional adapter 3

5

1

High-throughput

0.714

High

1287343

TAD2B
Transcriptional adapter 2-beta

5

4

High-throughput

0.714

High

1369189

KAT2A
Histone acetyltransferase KAT2A

5

14

High-throughput

0.714

High

1135651

AT7L3
Ataxin-7-like protein 3

5

1

Small-scale

0.712

High

1491369

TRRAP
Transformation/transcription domain-associated protein

4

4

High-throughput

0.699

High

1389718

SGF29
SAGA-associated factor 29

5

0

High-throughput

0.690

High

1337596

SP20H
Transcription factor SPT20 homolog

5

0

High-throughput

0.682

High

184759

ATX7
Ataxin-7

3

2

High-throughput

0.675

High

1462584

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

3

3

High-throughput

0.667

High

1148099

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.656

High

373649

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.640

High

319190

ST65G
STAGA complex 65 subunit gamma

3

0

High-throughput

0.638

High

999015

H31
Histone H3.1

1

5

High-throughput

0.618

High

1490784

WDR37
WD repeat-containing protein 37

1

3

High-throughput

0.618

High

212518

SPIT2
Kunitz-type protease inhibitor 2

3

1

High-throughput

0.609

High

538192

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.602

High

731751

STIP1
Stress-induced-phosphoprotein 1

2

0

High-throughput

0.602

High

1446159

ENY2
Transcription and mRNA export factor ENY2

2

0

High-throughput

0.585

High

1404710

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

397344

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

581800

MYOG
Myogenin

1

1

High-throughput

0.541

High

535959

MYH3
Myosin-3

1

2

High-throughput

0.536

High

854405

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

872952

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.536

High

1385416

ARMC5
Armadillo repeat-containing protein 5

1

1

High-throughput

0.536

High

1458875

FBLN5
Fibulin-5

1

1

High-throughput

0.536

High

1162096

H31T
Histone H3.1t

1

5

High-throughput

0.527

High

539652

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.513

High

1034857

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1164226

AOC3
Amine oxidase [copper-containing] 3

1

0

High-throughput

0.513

High

1249791

ELAP1
Endosome/lysosome-associated apoptosis and autophagy regulator 1

1

0

High-throughput

0.513

High

1394857

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.513

High

1416259

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.513

High

1434782

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

1461370

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

1491773

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

508926

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

1368544

CBP
CREB-binding protein

1

8

Small-scale

0.501

High

1460271

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

556974

MYH7
Myosin-7

1

2

High-throughput

0.489

High

608017

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

1

High-throughput

0.489

High

1431487

CAD23
Cadherin-23

1

2

High-throughput

0.489

High

1491527

PCDB7
Protocadherin beta-7

1

5

High-throughput

0.489

High

1491552

PCDB3
Protocadherin beta-3

1

5

High-throughput

0.489

High

1491587

PCDBB
Protocadherin beta-11

1

5

High-throughput

0.489

High

1491596

PCDGL
Protocadherin gamma-C4

1

4

High-throughput

0.489

High

1491798

MYH4
Myosin-4

1

2

High-throughput

0.489

High

67151

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

3

High-throughput

0.479

High

143360

NFIB
Nuclear factor 1 B-type

1

4

High-throughput

0.479

High

243449

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

260664

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

283582

TAD2A
Transcriptional adapter 2-alpha

1

5

High-throughput

0.479

High

474413

NFIC
Nuclear factor 1 C-type

1

4

High-throughput

0.479

High

487943

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

520491

ANDR
Androgen receptor

1

5

High-throughput

0.479

High

697003

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

831739

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

871807

RFX3
Transcription factor RFX3

1

1

High-throughput

0.479

High

881639

CDK8
Cyclin-dependent kinase 8

1

2

High-throughput

0.479

High

980634

H4
Histone H4

1

2

High-throughput

0.479

High

1088136

NFIA
Nuclear factor 1 A-type

1

4

High-throughput

0.479

High

1089084

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1110229

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.479

High

1133767

NFIX
Nuclear factor 1 X-type

1

4

High-throughput

0.479

High

1241535

EDC4
Enhancer of mRNA-decapping protein 4

1

1

High-throughput

0.479

High

1258113

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

3

High-throughput

0.479

High

1367716

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1368705

KAT6A
Histone acetyltransferase KAT6A

1

4

High-throughput

0.479

High

1401341

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.479

High

1405753

KLF6
Krueppel-like factor 6

1

4

High-throughput

0.479

High

1430667

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1452500

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1461651

YETS2
YEATS domain-containing protein 2

1

1

High-throughput

0.479

High

1462094

UBP18
Ubl carboxyl-terminal hydrolase 18

1

3

Small-scale

0.479

High

159940

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

377804

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

935374

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1315084

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.458

High

1397617

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1436251

CSR2B
Cysteine-rich protein 2-binding protein

1

0

High-throughput

0.458

High

1449175

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

1461621

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1491613

PCDGH
Protocadherin gamma-B5

1

6

High-throughput

0.445

High

412908

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

1213447

AT7L2
Ataxin-7-like protein 2

1

2

High-throughput

0.437

High

1256316

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1392520

A7L3B
Ataxin-7-like protein 3B

1

1

Small-scale

0.437

High

391534

FRIL
Ferritin light chain

1

0

High-throughput

0.426

High

944375

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.426

High

1047793

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.426

High

1273878

MICA3
[F-actin]-monooxygenase MICAL3

1

0

Small-scale

0.426

High

1491214

KAD6
Adenylate kinase isoenzyme 6

1

0

High-throughput

0.426

High

539758

ACHB
Acetylcholine receptor subunit beta

1

1

High-throughput

0.407

High

1330156

PCD20
Protocadherin-20

1

4

High-throughput

0.407

High

1491658

PCDG5
Protocadherin gamma-A5

1

6

High-throughput

0.407

High

1491689

PCDC2
Protocadherin alpha-C2

1

4

High-throughput

0.407

High

627591

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

2

0

High-throughput

0.318

High

1491843

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

0

High-throughput

0.313

High

318929

RHBT1
Rho-related BTB domain-containing protein 1

2

0

High-throughput

0.305

High

286745

STX11
Syntaxin-11

1

0

High-throughput

0.282

High

190531

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

289830

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

296752

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

596552

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1213738

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1249731

AEGP
Apical endosomal glycoprotein

1

0

High-throughput

0.279

Low

1325865

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1399659

OPALI
Opalin

1

0

High-throughput

0.279

Low

1436394

MANS1
MANSC domain-containing protein 1

1

0

High-throughput

0.279

Low

1454589

KLH14
Kelch-like protein 14

1

0

High-throughput

0.279

Low

294611

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1220919

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

1327310

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1430938

XYLT2
Xylosyltransferase 2

1

0

High-throughput

0.249

Low

165840

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

0

High-throughput

0.232

Low

239263

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.232

Low

727549

SC6A6
Sodium- and chloride-dependent taurine transporter

1

0

High-throughput

0.232

Low

1105265

S39A6
Zinc transporter ZIP6

1

0

High-throughput

0.232

Low

1313900

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low

1386851

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.232

Low

1399081

TMM74
Transmembrane protein 74

1

0

High-throughput

0.232

Low

1491127

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025