Protein: TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6 (TBP-associated factor 6) (TBP-associated factor 60 kDa) (TAFII-60) (TAFII60) (Transcription initiation factor TFIID subunit 6)

Gene: TAF6
Organism: Saccharomyces cerevisiae S288C
Interactions: 170
UniProt ID: P53040

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

793957

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

21

9

Small-scale

0.988

High

916602

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

15

8

Small-scale

0.986

High

916614

HFI1
SAGA complex subunit HFI1

12

1

Small-scale

0.977

High

916595

TAF8
Transcription initiation factor TFIID subunit 8

6

0

Small-scale

0.895

High

916579

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

3

2

Small-scale

0.847

High

916588

H3
Histone H3

2

5

Small-scale

0.776

High

762991

SPT7
SAGA complex subunit SPT7

22

14

Small-scale

0.766

High

858445

TAF1
Transcription initiation factor TFIID subunit 1

20

3

Small-scale

0.765

High

916590

ADA2
SAGA complex subunit ADA2

19

4

Small-scale

0.764

High

916596

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

16

5

Small-scale

0.762

High

916594

GCN5
Histone acetyltransferase GCN5

14

12

Small-scale

0.762

High

738165

NGG1
SAGA complex subunit NGG1

14

1

Small-scale

0.760

High

381568

H2B2
Histone H2B.2

2

2

Small-scale

0.759

High

916612

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

13

5

Small-scale

0.759

High

449463

SPT3
SAGA complex subunit SPT3

10

5

Small-scale

0.756

High

561502

TBP
TATA-box-binding protein

10

6

Small-scale

0.753

High

893316

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

10

3

Small-scale

0.753

High

676657

SGF29
SAGA complex subunit SGF29

8

1

Small-scale

0.750

High

916599

TAF11
Transcription initiation factor TFIID subunit 11

8

4

Small-scale

0.750

High

916582

SGF73
SAGA complex subunit SGF73

8

2

Small-scale

0.749

High

655628

TAF2
Transcription initiation factor TFIID subunit 2

8

1

Small-scale

0.748

High

916601

TAF7
Transcription initiation factor TFIID subunit 7

7

3

Small-scale

0.747

High

893366

TAF4
Transcription initiation factor TFIID subunit 4

7

3

Small-scale

0.746

High

548833

TAF13
Transcription initiation factor TFIID subunit 13

8

5

Small-scale

0.746

High

805198

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

7

4

Small-scale

0.745

High

916628

SUS1
SAGA complex subunit SUS1

6

1

Small-scale

0.732

High

807246

SPT8
SAGA complex subunit SPT8

13

0

Small-scale

0.728

High

898181

SPT20
SAGA complex subunit SPT20

13

0

Small-scale

0.728

High

381170

H2B1
Histone H2B.1

2

2

Small-scale

0.712

High

763349

TAF14
Transcription initiation factor TFIID subunit 14

5

1

Small-scale

0.709

High

916620

TAF3
Transcription initiation factor TFIID subunit 3

6

0

Small-scale

0.701

High

916592

SGF11
SAGA complex subunit SGF11

6

0

Small-scale

0.697

High

734447

BTAF1
TATA-binding protein-associated factor MOT1

3

4

Small-scale

0.640

High

452749

ADR1
Regulatory protein ADR1

2

1

Small-scale

0.621

High

725927

PSK1
Serine/threonine-protein kinase PSK1

2

1

High-throughput

0.621

High

817845

GLE2
mRNA export factor GLE2

1

2

High-throughput

0.618

High

419461

H2A1
Histone H2A.1

1

1

Small-scale

0.618

High

626522

AP1
AP-1-like transcription factor YAP1

2

0

High-throughput

0.602

High

579746

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.601

High

754224

MSN4
Zinc finger protein MSN4

2

1

High-throughput

0.601

High

460352

SYV
Valine--tRNA ligase, mitochondrial

2

0

High-throughput

0.595

High

541286

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase

2

0

High-throughput

0.595

High

368912

SYMC
Methionine--tRNA ligase, cytoplasmic

2

1

High-throughput

0.588

High

694594

SPT5
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

689779

INO2
Protein INO2

2

0

Small-scale

0.577

High

408428

GAL4
Regulatory protein GAL4

2

2

Small-scale

0.576

High

395256

GCN4
General control transcription factor GCN4

2

0

Small-scale

0.576

High

916627

H2AZ
Histone H2A.Z

1

2

High-throughput

0.575

High

823002

ATAD2
ATPase histone chaperone YTA7

2

1

High-throughput

0.571

High

671425

RNA14
mRNA 3'-end-processing protein RNA14

2

0

High-throughput

0.563

High

740468

MED22
Mediator of RNA polymerase II transcription subunit 22

2

0

High-throughput

0.563

High

916610

MED7
Mediator of RNA polymerase II transcription subunit 7

2

0

High-throughput

0.563

High

707658

TF2B
Transcription initiation factor IIB

2

0

Small-scale

0.559

High

916625

NOT5
General negative regulator of transcription subunit 5

2

0

Small-scale

0.559

High

777082

BDF1
Bromodomain-containing factor 1

1

13

Small-scale

0.554

High

548786

MCM1
Pheromone receptor transcription factor

2

0

High-throughput

0.547

High

670931

SIS1
Protein SIS1

2

0

High-throughput

0.547

High

727183

HS104
Heat shock protein 104

2

0

High-throughput

0.547

High

736681

ASF1
Histone chaperone ASF1

2

0

Small-scale

0.547

High

916619

RIO1
Serine/threonine-protein kinase RIO1

2

0

High-throughput

0.547

High

359037

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.536

High

359503

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.536

High

383159

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.536

High

393043

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.536

High

597213

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

722102

XPO1
Exportin-1

1

1

High-throughput

0.536

High

916618

HAL9
Halotolerance protein 9

1

2

High-throughput

0.536

High

916622

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.536

High

916617

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.515

High

445355

CDC31
Cell division control protein 31

1

0

Small-scale

0.513

High

553634

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.513

High

569821

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

572620

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.513

High

590677

HSP26
Heat shock protein 26

1

0

High-throughput

0.513

High

639451

DIT1
Spore wall maturation protein DIT1

1

0

High-throughput

0.513

High

670298

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.513

High

740192

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.513

High

750735

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.513

High

757991

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.513

High

781223

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.513

High

822418

PRS4
26S proteasome regulatory subunit 4 homolog

1

0

High-throughput

0.513

High

825286

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.513

High

916593

MTG1
Mitochondrial GTPase 1

1

0

High-throughput

0.513

High

916607

SUB2
ATP-dependent RNA helicase SUB2

1

0

High-throughput

0.513

High

916609

THP1
Nuclear mRNA export protein THP1

1

0

Small-scale

0.513

High

877586

RFX1
RFX-like DNA-binding protein RFX1

1

1

Small-scale

0.501

High

550064

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.494

High

427589

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.489

High

427724

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.489

High

528846

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.489

High

509648

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

511947

RS30A
Small ribosomal subunit protein eS30A

1

1

High-throughput

0.479

High

744321

CHD1
Chromo domain-containing protein 1

1

2

Small-scale

0.479

High

829873

SAS2
Histone acetyltransferase SAS2

1

1

Small-scale

0.479

High

916587

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

916598

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

403583

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

435230

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

511233

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.458

High

513531

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.458

High

513725

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.458

High

514319

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

594471

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

689558

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

735068

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747953

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

753475

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

763940

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

764120

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

800733

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.458

High

812489

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

826663

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

858344

SAC3
Nuclear mRNA export protein SAC3

1

0

Small-scale

0.458

High

865675

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

916580

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.458

High

916585

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

916603

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

916604

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

916615

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

916616

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

382224

H4
Histone H4

1

2

High-throughput

0.445

High

436463

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.445

High

448195

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

488975

SWI6
Regulatory protein SWI6

1

1

High-throughput

0.445

High

511988

RS30B
Small ribosomal subunit protein eS30B

1

1

High-throughput

0.445

High

671538

SWI4
Regulatory protein SWI4

1

1

High-throughput

0.445

High

741986

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

754167

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

781767

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

819274

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

916586

CRZ1
Transcriptional regulator CRZ1

1

1

High-throughput

0.445

High

916589

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

12

High-throughput

0.445

High

916591

HOS3
Histone deacetylase HOS3

1

3

High-throughput

0.445

High

584452

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.438

High

432637

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

483793

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.426

High

531809

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

645623

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

743607

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.426

High

820425

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

835837

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

916597

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.426

High

916605

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.426

High

916608

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

916621

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.426

High

916623

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

916613

RCN2
Regulator of calcineurin 2

1

0

High-throughput

0.282

High

267947

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

1

0

High-throughput

0.279

Low

358282

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.279

Low

386791

TBB
Tubulin beta chain

1

0

High-throughput

0.279

Low

417146

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.279

Low

427363

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

484779

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

518338

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.279

Low

656334

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

High-throughput

0.279

Low

723190

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.279

Low

866150

CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial

1

0

High-throughput

0.279

Low

916581

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.279

Low

916583

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.279

Low

916606

MRL1
Mannose 6-phosphate receptor-like protein 1

1

0

High-throughput

0.279

Low

916611

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

1

0

High-throughput

0.279

Low

916624

NOP58
Nucleolar protein 58

1

0

High-throughput

0.279

Low

916626

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.279

Low

916629

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.279

Low

916600

GFD1
mRNA transport factor GFD1

1

0

High-throughput

0.265

Low

585314

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

858492

TFC5
Transcription factor TFIIIB component B''

1

0

High-throughput

0.249

Low

916584

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

825588

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025