HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0030027 - lamellipodium GO:0045202 - synapse
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 474
+	Hs
		930051 ACTG_HUMAN (1-375): 0: 601: 98.93		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932449 ACTC_HUMAN (2-375): 0: 592: 94.12		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932355 ACTC_HUMAN (2-375): 0: 592: 94.12		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		903316 POTEE_HUMAN (1-375): 0: 736: 92.00		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		903280 ACTBL_HUMAN (2-375): 0: 735: 91.71		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		932318 ACTC_HUMAN (2-375): 0: 592: 94.12		SNR40_HUMAN (160-435): 1.36e-38: 145: 11.87
+	Hs
		932185 ACTC_HUMAN (2-375): 0: 592: 94.12		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		891943 ACTB_HUMAN (1-375): 0: 603: 100.00		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		929956 ACTG_HUMAN (1-375): 0: 601: 98.93		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		884627 ACTB_HUMAN (1-375): 0: 603: 100.00		CORO7_HUMAN (2-203): 2.45e-23: 105: 12.22
+	Sc
		887686 ACT_YEAST (1-375): 0: 591: 88.80		CORO_YEAST (2-228): 2.02e-24: 108: 12.16
+	Hs
		891660 ACTB_HUMAN (1-375): 0: 603: 100.00		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		903110 ACTG_HUMAN (1-375): 0: 601: 98.93		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39