HitPredict

Interactor 1: SEM1 (P60896)
26S proteasome complex subunit SEM1 (26S proteasome complex subunit DSS1) (Deleted in split hand/split foot protein 1) (Split hand/foot deleted protein 1) (Split hand/foot malformation type 1 protein)
Gene: SEM1

Interactor 2: LENG8 (Q96PV6)
Leukocyte receptor cluster member 8
Gene: LENG8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	16239144, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DSS1_SEM1~SAC3_GANP
Common GO terms	GO:0032991 - protein-containing complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 70 Hs			1 800
+	Hs
		231290 SEM1_HUMAN (1-70): 3.65e-23: 84.7: 100.00		GANP_HUMAN (3-783): 3.03e-127: 421: 14.60
+	Hs
		101801 SEM1_HUMAN (1-70): 3.65e-23: 84.7: 100.00		F8WC89_HUMAN (519-789): 1.13e-55: 197: 19.74
+	Hs
		123893 SEM1_HUMAN (1-70): 3.65e-23: 84.7: 100.00		SPT5H_HUMAN (3-237): 1.72e-12: 73.5: 17.23