HitPredict

Interactor 1: PSA6 (P60900)
Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)
Gene: PSMA6

Interactor 2: PSME1 (Q06323)
Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha)
Gene: PSME1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 35271311, 12419264
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PA28_beta~Proteasome, PA28_beta~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0070062 - extracellular exosome
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 246
Hs

1 249
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Last updated: 15 Jul 2024