HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: BNIP2 (Q12982)
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Gene: BNIP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	10799524, 10954711, 10551883
Identification Methods	pull down, enzymatic study, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 314
+	Hs
		1183436 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		BNIPL_HUMAN (4-309): 7.97e-119: 347: 45.59
+	Hs
		564492 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Dm
		776920 RAC1_DROME (1-191): 1.02e-81: 242: 69.27		RG68F_DROME (52-313): 1.97e-67: 220: 25.19
+	Hs
		993069 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Mm
		925791 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		RHG01_MOUSE (96-312): 3.12e-64: 210: 33.78
+	Hs
		925227 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Mm
		892723 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		RHG01_MOUSE (96-312): 3.12e-64: 210: 33.78
+	Mm
		1125742 RHOA_MOUSE (5-191): 9.99e-82: 242: 53.48		RHG01_MOUSE (96-312): 3.12e-64: 210: 33.78
+	Hs
		893937 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Hs
		950946 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Hs
		900412 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Hs
		545341 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Hs
		436273 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67
+	Hs
		892334 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		RHG01_HUMAN (96-312): 8.89e-64: 209: 34.67