HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LBR (Q14739)
Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase)
Gene: LBR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 615
+	Hs
		1058818 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		925284 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		951000 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		900478 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		545383 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		436305 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		892377 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		564719 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		1330969 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		925696 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		894549 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		951430 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		901010 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		545679 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		436556 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		892655 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Hs
		1183589 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00