HitPredict

Interactor 1: GDIB (P50395)
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)
Gene: GDI2

Interactor 2: RAB9A (P51151)
Ras-related protein Rab-9A (EC 3.6.5.2)
Gene: RAB9A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.948

Property	Details
Experiments	10512627, 35271311, 28514442, 34079125, 33961781, 38334954
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0015031 - protein transport GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 201
+	Hs
		894551 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB35_HUMAN (1-201): 2.77e-88: 259: 36.72
+	Hs
		724479 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB35_HUMAN (1-201): 2.77e-88: 259: 36.72
+	Hs
		724451 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB9A_HUMAN (1-201): 3.87e-83: 246: 100.00
+	Hs
		894521 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB8A_HUMAN (1-199): 1.14e-79: 238: 35.12
+	Hs
		894530 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1A_HUMAN (2-201): 4.32e-79: 236: 32.68
+	Hs
		894580 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB8B_HUMAN (1-199): 3.66e-78: 234: 35.12
+	Hs
		894591 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1B_HUMAN (2-201): 1.31e-77: 232: 32.02
+	Mm
		894618 GDIA_MOUSE (1-444): 0: 717: 87.39		RAB1A_MOUSE (2-201): 4.32e-79: 236: 32.68
+	Hs
		724456 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB8A_HUMAN (1-199): 1.14e-79: 238: 35.12
+	Hs
		724464 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1A_HUMAN (2-201): 4.32e-79: 236: 32.68
+	Hs
		724502 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB8B_HUMAN (1-199): 3.66e-78: 234: 35.12
+	Hs
		894529 GDIB_HUMAN (1-445): 0: 722: 100.00		RB11A_HUMAN (3-201): 1.32e-74: 225: 35.38
+	Hs
		724515 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1B_HUMAN (2-201): 1.31e-77: 232: 32.02
+	Hs
		894509 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB7A_HUMAN (2-200): 5.13e-74: 223: 50.24
+	Hs
		724463 GDIA_HUMAN (1-444): 0: 714: 86.49		RB11A_HUMAN (3-201): 1.32e-74: 225: 35.38
+	Hs
		724450 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB7A_HUMAN (2-200): 5.13e-74: 223: 50.24
+	Dm
		197101 Q9VLB7_DROME (1-440): 0: 662: 67.80		O18332_DROME (2-201): 2.2e-76: 229: 32.35
+	Hs
		894553 GDIB_HUMAN (1-445): 0: 722: 100.00		RB11B_HUMAN (7-181): 2.02e-38: 133: 39.56
+	Hs
		724480 GDIA_HUMAN (1-444): 0: 714: 86.49		RB11B_HUMAN (7-181): 2.02e-38: 133: 39.56
+	Dm
		197373 Q9VLB7_DROME (1-440): 0: 662: 67.80		O18335_DROME (7-172): 3.8e-39: 135: 40.72