HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: MELPH (Q9BV36)
Melanophilin (Exophilin-3) (Slp homolog lacking C2 domains a) (SlaC2-a) (Synaptotagmin-like protein 2a)
Gene: MLPH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11773082
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 600
+	Hs
		895496 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		SYTL3_HUMAN (1-390): 7.31e-82: 270: 19.47
+	Hs
		1273004 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		SYTL4_HUMAN (1-251): 2.21e-67: 233: 20.85
+	Hs
		894790 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		SYTL4_HUMAN (1-251): 2.21e-67: 233: 20.85
+	Hs
		914240 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		SYTL5_HUMAN (2-403): 5.42e-78: 263: 18.69
+	Mm
		877205 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		SYTL4_MOUSE (1-250): 5.54e-67: 232: 21.62
+	Mm
		812770 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RP3A_MOUSE (8-264): 5.78e-64: 224: 17.63
+	Hs
		1273014 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RP3A_HUMAN (8-267): 9.04e-57: 204: 14.93
+	Hs
		894828 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RP3A_HUMAN (8-267): 9.04e-57: 204: 14.93
+	Hs
		914274 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		SYTL4_HUMAN (1-251): 2.21e-67: 233: 20.85
+	Mm
		877194 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RPH3L_MOUSE (10-279): 8.35e-61: 206: 15.33
+	Mm
		877203 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RIMS2_MOUSE (3-475): 4.6e-55: 204: 14.71
+	Mm
		895586 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RIMS1_MOUSE (1-252): 2.63e-41: 162: 13.48