HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	30357346
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 793
+	Hs
		849419 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		UHRF1_HUMAN (1-793): 0: 893: 100.00
+	Hs
		919835 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		UHRF1_HUMAN (1-793): 0: 893: 100.00
+	Hs
		895889 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		UHRF1_HUMAN (1-793): 0: 893: 100.00
+	Hs
		1299596 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		UHRF2_HUMAN (1-793): 0: 774: 53.01
+	Hs
		849415 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		UHRF2_HUMAN (1-793): 0: 774: 53.01
+	Hs
		919833 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		UHRF2_HUMAN (1-793): 0: 774: 53.01
+	Hs
		895886 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		UHRF2_HUMAN (1-793): 0: 774: 53.01
+	Zm
		13330 A0A1D6FSE0_MAIZE (4-149): 7.15e-81: 237: 46.58		A0A1D6FSK8_MAIZE (361-667): 2.49e-68: 240: 20.50
+	Hs
		1052807 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08
+	Hs
		849330 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08
+	Hs
		919727 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08
+	Hs
		919886 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		PHRF1_HUMAN (318-423): 2.27e-19: 96.1: 32.50
+	Hs
		895794 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08
+	Hs
		896442 UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08