HitPredict

Interactor 1: RAB14 (P61106)
Ras-related protein Rab-14 (EC 3.6.5.2)
Gene: RAB14

Interactor 2: RTN4 (Q9NQC3)
Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5)
Gene: RTN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1192
+	Hs
		895290 RAB2A_HUMAN (8-195): 6.73e-96: 280: 62.77		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		592029 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		918953 RAB1A_HUMAN (1-215): 1.44e-87: 258: 42.33		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		914380 RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		1079968 RB11B_HUMAN (1-215): 1.84e-84: 251: 44.65		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		1328148 RAB1B_HUMAN (4-215): 8.23e-84: 249: 40.57		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Mm
		1265279 RAB4B_MOUSE (8-215): 9.53e-87: 256: 57.94		RTN4_MOUSE (16-1192): 1.92e-89: 315: 70.88
+	At
		656920 RAE1C_ARATH (7-214): 1.25e-93: 274: 41.63		RTNLD_ARATH (992-1192): 1.36e-70: 238: 22.75
+	At
		221744 RAA1E_ARATH (1-214): 3.45e-82: 245: 43.06		RTNLB_ARATH (920-1192): 1.01e-73: 248: 19.36
+	Hs
		307017 RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54		RTN3_HUMAN (269-1191): 7.4e-55: 210: 22.06
+	At
		1324948 RAD2B_ARATH (4-214): 4.02e-83: 247: 40.76		RTNLH_ARATH (990-1188): 8.95e-61: 210: 18.54