Protein: TIFA
TRAF-interacting protein with FHA domain-containing protein A (Putative MAPK-activating protein PM14) (Putative NF-kappa-B-activating protein 20) (TRAF2-binding protein)

Gene: TIFA
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q96CG3

Gene Ontology (top 5):
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction
GO:0033209 - tumor necrosis factor-mediated signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1286776

TIFA
TRAF-interacting protein with FHA domain-containing protein A

2

2

Small-scale

0.768

High

1169464

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

2

2

Small-scale

0.754

High

1020857

TRAF2
TNF receptor-associated factor 2

9

5

Small-scale

0.754

High

871458

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

0

High-throughput

0.742

High

1286786

TRAF6
TNF receptor-associated factor 6

6

7

Small-scale

0.737

High

132980

SDCB1
Syntenin-1

4

2

High-throughput

0.707

High

1286784

SDCB2
Syntenin-2

3

3

High-throughput

0.688

High

1233851

ARG39
Rho guanine nucleotide exchange factor 39

2

0

High-throughput

0.678

High

1286782

AP1M1
AP-1 complex subunit mu-1

4

0

High-throughput

0.675

High

702121

RL9
Large ribosomal subunit protein uL6

3

0

High-throughput

0.646

High

1286785

NXF1
Nuclear RNA export factor 1

3

0

High-throughput

0.646

High

848444

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

Small-scale

0.618

High

151127

DVL2
Segment polarity protein dishevelled homolog DVL-2

2

0

High-throughput

0.613

High

1252384

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.608

High

234352

GSDME
Gasdermin-E

2

0

High-throughput

0.580

High

1144743

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

0

High-throughput

0.580

High

1286778

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1023754

TRAF1
TNF receptor-associated factor 1

1

5

High-throughput

0.560

High

1036317

BIRC2
Baculoviral IAP repeat-containing protein 2

2

0

Small-scale

0.559

High

312764

TFIP8
Tumor necrosis factor alpha-induced protein 8

1

0

High-throughput

0.549

High

599706

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

0

Small-scale

0.537

High

1173004

NUD18
8-oxo-dGDP phosphatase NUDT18

1

0

High-throughput

0.518

High

1286783

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.518

High

672715

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.513

High

1232891

LNX2
Ligand of Numb protein X 2

1

1

High-throughput

0.512

High

1135884

TUT4
Terminal uridylyltransferase 4

1

0

Small-scale

0.493

High

1286779

ALPK1
Alpha-protein kinase 1

1

0

Small-scale

0.480

High

1024729

TRAF3
TNF receptor-associated factor 3

1

7

Small-scale

0.479

High

1027748

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

Small-scale

0.479

High

1286780

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

Small-scale

0.479

High

476173

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

507177

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

Small-scale

0.458

High

1201867

TAXB1
Tax1-binding protein 1

1

0

Small-scale

0.458

High

1286777

OPTN
Optineurin

1

0

Small-scale

0.458

High

883120

DSCR6
Protein ripply3

3

0

High-throughput

0.346

High

1244885

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

1286781

THIOM
Thioredoxin, mitochondrial

1

0

High-throughput

0.299

High

555585

H2AX
Histone H2AX

1

0

Small-scale

0.249

Low

824265

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

Small-scale

0.249

Low

867886

HIRA
Protein HIRA

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024