Protein: MEF2A
Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1)

Gene: MEF2A
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q02078

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1034680

MEF2D
Myocyte-specific enhancer factor 2D

4

19

Small-scale

0.895

High

1034670

MEF2B
Myocyte-specific enhancer factor 2B

3

18

High-throughput

0.861

High

1034672

MEF2C
Myocyte-specific enhancer factor 2C

2

18

High-throughput

0.811

High

940921

HDAC4
Histone deacetylase 4

6

20

Small-scale

0.735

High

1034698

PITX2
Pituitary homeobox 2

1

1

Small-scale

0.713

High

1034706

HDAC5
Histone deacetylase 5

4

20

Small-scale

0.700

High

893683

MEOX1
Homeobox protein MOX-1

1

3

High-throughput

0.698

High

1034694

HDAC7
Histone deacetylase 7

4

20

Small-scale

0.680

High

896686

ASCL1
Achaete-scute homolog 1

2

4

Small-scale

0.625

High

991297

SUMO1
Small ubiquitin-related modifier 1

2

1

Small-scale

0.624

High

1034673

EP300
Histone acetyltransferase p300

2

5

Small-scale

0.624

High

1034677

MK07
Mitogen-activated protein kinase 7

2

16

Small-scale

0.614

High

1034683

MK14
Mitogen-activated protein kinase 14

2

14

Small-scale

0.602

High

1034705

HDAC9
Histone deacetylase 9

2

20

Small-scale

0.595

High

872219

SOX2
Transcription factor SOX-2

2

4

High-throughput

0.584

High

269176

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1034669

MEF2A
Myocyte-specific enhancer factor 2A

1

18

High-throughput

0.575

High

993504

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.568

High

224692

ACTN4
Alpha-actinin-4

1

1

Small-scale

0.561

High

354056

HAND1
Heart- and neural crest derivatives-expressed protein 1

1

3

Small-scale

0.561

High

1034681

SMAD2
Mothers against decapentaplegic homolog 2

1

2

Small-scale

0.561

High

429751

JUN
Transcription factor Jun

1

4

High-throughput

0.554

High

533269

THA
Thyroid hormone receptor alpha

1

0

Small-scale

0.537

High

253245

REV3L
DNA polymerase zeta catalytic subunit

1

1

High-throughput

0.536

High

605072

JUND
Transcription factor JunD

1

5

High-throughput

0.536

High

605251

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

4

High-throughput

0.536

High

617150

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

5

High-throughput

0.536

High

926647

HIRA
Protein HIRA

1

2

High-throughput

0.536

High

980704

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.536

High

1034684

MAPK3
MAP kinase-activated protein kinase 3

1

1

High-throughput

0.536

High

1034695

H2B1A
Histone H2B type 1-A

1

1

High-throughput

0.536

High

1034707

CABIN
Calcineurin-binding protein cabin-1

1

3

High-throughput

0.536

High

1034682

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.518

High

932567

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.513

High

1034685

H31T
Histone H3.1t

1

0

High-throughput

0.513

High

1034687

TTLL7
Tubulin polyglutamylase TTLL7

1

0

High-throughput

0.513

High

1034688

SETX
Probable helicase senataxin

1

0

High-throughput

0.513

High

1034699

ZCPW1
Zinc finger CW-type PWWP domain protein 1

1

0

High-throughput

0.513

High

1034700

SH2B1
SH2B adapter protein 1

1

0

High-throughput

0.513

High

1034696

ERBIN
Erbin

1

0

Small-scale

0.505

High

581763

MYOG
Myogenin

1

6

Small-scale

0.501

High

1034704

DNM3L
DNA

1

1

Small-scale

0.501

High

1034708

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

1

High-throughput

0.494

High

1034703

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.493

High

1034686

KLC3
Kinesin light chain 3

1

1

High-throughput

0.489

High

1034701

KLC4
Kinesin light chain 4

1

1

High-throughput

0.489

High

142946

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

172717

XPO1
Exportin-1

1

1

High-throughput

0.479

High

188245

HDAC3
Histone deacetylase 3

1

6

Small-scale

0.479

High

473924

NFIC
Nuclear factor 1 C-type

1

4

High-throughput

0.479

High

519955

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

628756

TBP
TATA-box-binding protein

1

1

Small-scale

0.479

High

886771

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.479

High

964230

SUMO2
Small ubiquitin-related modifier 2

1

1

Small-scale

0.479

High

967672

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

High-throughput

0.479

High

1034671

KPCT
Protein kinase C theta type

1

1

Small-scale

0.479

High

1034675

NFIA
Nuclear factor 1 A-type

1

7

High-throughput

0.479

High

1034676

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1034678

HDAC1
Histone deacetylase 1

1

13

Small-scale

0.479

High

1034693

SP7
Transcription factor Sp7

1

6

High-throughput

0.479

High

1034697

PHB2
Prohibitin-2

1

1

Small-scale

0.479

High

1034679

VGLL4
Transcription cofactor vestigial-like protein 4

1

0

Small-scale

0.460

High

431789

ITB1
Integrin beta-1

1

0

High-throughput

0.458

High

443052

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.458

High

485078

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

Small-scale

0.458

High

984080

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

Small-scale

0.458

High

1034689

TAF8
Transcription initiation factor TFIID subunit 8

1

0

Small-scale

0.458

High

1034691

ZN420
Zinc finger protein 420

1

0

High-throughput

0.458

High

952115

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.391

High

1034674

CCD15
Coiled-coil domain-containing protein 15

1

0

High-throughput

0.279

Low

1034690

XYLT1
Xylosyltransferase 1

1

0

High-throughput

0.279

Low

1034692

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1034702

GBG12

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025