Protein: TWST2
Twist-related protein 2 (Class A basic helix-loop-helix protein 39) (bHLHa39) (Dermis-expressed protein 1) (Dermo-1)

Gene: TWST2, TWIST2
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q8WVJ9

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1358158

HTF4
Transcription factor 12

5

20

High-throughput

0.933

High

587158

ITF2
Transcription factor 4

3

20

High-throughput

0.882

High

587507

TFE2
Transcription factor E2-alpha

3

20

High-throughput

0.858

High

787882

SRBP1
Sterol regulatory element-binding protein 1

1

11

Small-scale

0.680

High

1358157

FER3L
Fer3-like protein

1

19

High-throughput

0.621

High

1151966

TWST1
Twist-related protein 1

1

20

Small-scale

0.618

High

1358159

CCM2
Cerebral cavernous malformations 2 protein

2

0

High-throughput

0.607

High

1358160

GLIS2
Zinc finger protein GLIS2

2

7

High-throughput

0.606

High

599303

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

2

2

High-throughput

0.576

High

855703

CRK
Adapter molecule crk

2

5

High-throughput

0.576

High

1358155

NACC2
Nucleus accumbens-associated protein 2

1

4

High-throughput

0.536

High

1358156

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

10

High-throughput

0.536

High

1358161

ZBT20
Zinc finger and BTB domain-containing protein 20

1

4

High-throughput

0.536

High

578309

ETS2
Protein C-ets-2

1

14

Small-scale

0.534

High

843806

HD
Huntingtin

1

2

High-throughput

0.515

High

1123735

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.515

High

791575

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

927450

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

1358162

ATX10
Ataxin-10

1

0

High-throughput

0.493

High

414296

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

714296

PML
Protein PML

1

10

Small-scale

0.479

High

1055027

MEF2C
Myocyte-specific enhancer factor 2C

1

8

Small-scale

0.479

High

1115320

CUL4B
Cullin-4B

1

5

Small-scale

0.479

High

47384

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.470

High

369714

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025