HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	32707033, 34591612
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006468 - protein phosphorylation and 1 others more... GO:0007165 - signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 433
+	Hs
		1024165 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		STK11_HUMAN (1-433): 8.74e-141: 411: 100.00
+	Hs
		1079140 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		STK11_HUMAN (1-433): 8.74e-141: 411: 100.00
+	Hs
		121746 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		AAPK1_HUMAN (46-314): 3.36e-47: 172: 36.67
+	Hs
		121713 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		AAPK2_HUMAN (46-314): 6.65e-45: 165: 36.30