HitPredict

Interactor 1: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Interactor 2: NRBP2 (Q9NSY0)
Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16)
Gene: NRBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 501
+	Hs
		914159 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		MARK2_HUMAN (11-490): 6.7e-115: 358: 13.73
+	Hs
		681775 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		AKT1_HUMAN (9-367): 5.98e-119: 359: 14.63
+	Hs
		925384 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		MARK2_HUMAN (11-490): 6.7e-115: 358: 13.73
+	Hs
		320512 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		OXSR1_HUMAN (23-501): 1.52e-115: 352: 14.87
+	Hs
		925702 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		STK39_HUMAN (34-501): 3.81e-114: 349: 14.78
+	Hs
		349425 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		MARK2_HUMAN (11-490): 6.7e-115: 358: 13.73
+	Hs
		349916 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		AKT2_HUMAN (3-354): 1.14e-118: 358: 15.07
+	Hs
		350286 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		MARK2_HUMAN (11-490): 6.7e-115: 358: 13.73
+	Rn
		871319 RAC1_RAT (1-184): 1.05e-68: 209: 27.55		AAPK1_RAT (37-476): 4.69e-99: 311: 15.25
+	Mm
		103566 RAC1_MOUSE (1-184): 1.05e-68: 209: 27.55		G5E884_MOUSE (4-317): 4.59e-76: 250: 23.57
+	Hs
		925244 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		PAK1_HUMAN (4-317): 4.56e-76: 250: 23.57
+	Mm
		292040 RAC1_MOUSE (1-184): 1.05e-68: 209: 27.55		PAK1_MOUSE (4-317): 1.49e-75: 249: 23.57
+	Hs
		897884 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		PAK2_HUMAN (4-317): 7.65e-70: 233: 22.85
+	Hs
		277602 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		PAK3_HUMAN (10-317): 4.15e-73: 243: 23.39
+	Mm
		925809 RAC1_MOUSE (1-184): 1.05e-68: 209: 27.55		PAK2_MOUSE (4-317): 1.6e-70: 235: 22.85
+	Hs
		925245 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		PAK2_HUMAN (4-317): 7.65e-70: 233: 22.85
+	Hs
		1026199 RIT1_HUMAN (2-180): 7.98e-57: 179: 49.16		PAK1_HUMAN (4-317): 4.56e-76: 250: 23.57
+	Hs
		350133 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		PAK2_HUMAN (4-317): 7.65e-70: 233: 22.85
+	Hs
		925648 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		PAK6_HUMAN (41-308): 7.79e-09: 60.1: 24.31
+	Hs
		349667 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		PAK6_HUMAN (41-308): 7.79e-09: 60.1: 24.31