HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: EGLN3 (Q9H6Z9)
Prolyl hydroxylase EGLN3 (EC 1.14.11.-) (Egl nine homolog 3) (EC 1.14.11.29) (HPH-1) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-PH3) (HIF-prolyl hydroxylase 3) (HPH-3) (Prolyl hydroxylase domain-containing protein 3) (PHD3)
Gene: EGLN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26972000
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 239
+	Hs
		1097165 MK07_HUMAN (12-372): 2.67e-132: 399: 29.75		EGLN3_HUMAN (1-239): 5.69e-162: 449: 100.00
+	Hs
		668030 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		EGLN3_HUMAN (1-239): 5.69e-162: 449: 100.00
+	Hs
		1435376 CDK12_HUMAN (16-371): 2.05e-123: 390: 42.54		EGLN3_HUMAN (1-239): 5.69e-162: 449: 100.00
+	Hs
		703711 MK01_HUMAN (5-359): 5.51e-133: 386: 30.99		EGLN3_HUMAN (1-239): 5.69e-162: 449: 100.00
+	Hs
		443522 CDK1_HUMAN (16-315): 1.05e-123: 359: 40.40		EGLN3_HUMAN (1-239): 5.69e-162: 449: 100.00
+	Hs
		1025510 CDK5_HUMAN (16-317): 5.5e-118: 345: 39.93		EGLN3_HUMAN (1-239): 5.69e-162: 449: 100.00
+	Hs
		667988 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		EGLN2_HUMAN (12-226): 6.92e-132: 379: 61.86