HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (EC 3.6.1.-) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: TCAB1 (Q9BUR4)
Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein antisense to TP53 gene) (WRAP53beta)
Gene: WRAP53

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	26496610, 25467444
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005829 - cytosol GO:0032212 - positive regulation of telomere maintenance via telomerase
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 548
+	Hs
		1407541 TCPH_HUMAN (9-538): 0: 564: 26.39		TCAB1_HUMAN (1-535): 4.04e-107: 333: 98.33
+	Hs
		899135 TCPQ_HUMAN (1-548): 0: 616: 100.00		POC1A_HUMAN (315-548): 1.41e-55: 194: 14.53
+	Hs
		209223 TCPQ_HUMAN (1-548): 0: 616: 100.00		PRP4_HUMAN (327-548): 1.4e-40: 155: 15.28
+	Hs
		1334162 TCPH_HUMAN (9-538): 0: 564: 26.39		POC1A_HUMAN (315-548): 1.41e-55: 194: 14.53
+	Hs
		898984 TCPQ_HUMAN (1-548): 0: 616: 100.00		GBB2_HUMAN (341-546): 1.75e-33: 132: 12.62
+	Hs
		209325 TCPH_HUMAN (9-538): 0: 564: 26.39		PRP4_HUMAN (327-548): 1.4e-40: 155: 15.28
+	Hs
		1291941 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR5B_HUMAN (359-541): 7.53e-42: 154: 12.02
+	Hs
		209218 TCPG_HUMAN (10-547): 0: 558: 28.21		PRP4_HUMAN (327-548): 1.4e-40: 155: 15.28
+	Hs
		882014 TCPG_HUMAN (10-547): 0: 558: 28.21		WDR5B_HUMAN (359-541): 7.53e-42: 154: 12.02
+	Hs
		1407533 TCPH_HUMAN (9-538): 0: 564: 26.39		TBL1Y_HUMAN (305-548): 8.78e-38: 147: 10.85
+	Hs
		898980 TCPQ_HUMAN (1-548): 0: 616: 100.00		WDR5_HUMAN (455-548): 1.2e-18: 89.3: 9.57
+	Hs
		899171 TCPQ_HUMAN (1-548): 0: 616: 100.00		SNR40_HUMAN (445-548): 3.26e-18: 88.1: 11.43
+	Hs
		984251 TCPH_HUMAN (9-538): 0: 564: 26.39		GBB2_HUMAN (341-546): 1.75e-33: 132: 12.62
+	Hs
		983563 TCPH_HUMAN (9-538): 0: 564: 26.39		GBB1_HUMAN (294-526): 1.32e-32: 129: 10.68
+	Hs
		845257 TCPG_HUMAN (10-547): 0: 558: 28.21		LIS1_HUMAN (407-548): 3.49e-33: 132: 14.79
+	Hs
		881865 TCPG_HUMAN (10-547): 0: 558: 28.21		GBB2_HUMAN (341-546): 1.75e-33: 132: 12.62
+	Hs
		881864 TCPG_HUMAN (10-547): 0: 558: 28.21		GBB1_HUMAN (294-526): 1.32e-32: 129: 10.68
+	Hs
		1407594 TCPH_HUMAN (9-538): 0: 564: 26.39		NLE1_HUMAN (51-257): 5.05e-27: 116: 11.59
+	Hs
		965190 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR5_HUMAN (455-548): 1.2e-18: 89.3: 9.57
+	Hs
		881861 TCPG_HUMAN (10-547): 0: 558: 28.21		WDR5_HUMAN (455-548): 1.2e-18: 89.3: 9.57