HitPredict

Interactor 1: ISL1 (P61371)
Insulin gene enhancer protein ISL-1 (Islet-1)
Gene: ISL1

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36950384, 37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007409 - axonogenesis GO:0043524 - negative regulation of neuron apoptotic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 349 Hs			1 1343
+	Hs
		1283494 ISL2_HUMAN (1-349): 3.08e-80: 250: 73.35		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1189158 PRIC2_HUMAN (1-336): 2.15e-39: 150: 15.08		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		100062 ABLM1_MOUSE (7-305): 6.9e-29: 119: 14.20		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		100030 PRIC2_MOUSE (4-69): 5.18e-09: 59.5: 19.12		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		598447 LIMK2_HUMAN (17-227): 5.7e-68: 226: 25.94		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		150537 ABLM1_HUMAN (2-339): 4.04e-22: 99.7: 12.87		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21