Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: KANL1 (Q7Z3B3)
KAT8 regulatory NSL complex subunit 1 (MLL1/MLL complex subunit KANSL1) (MSL1 homolog 1) (hMSL1v1) (NSL complex protein NSL1) (Non-specific lethal 1 homolog)
Gene: KANSL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 26186194, 24788516, 28514442, 27705803, 33961781, 33472061, 24981860, 19854137, 15960975
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, anti tag coimmunoprecipitation, tandem affinity purification, isothermal titration calorimetry, molecular sieving
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000123 - histone acetyltransferase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0044545 - NSL complex
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 334
Hs

1 1105
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024