HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PDE3B (Q13370)
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)
Gene: PDE3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1112
+	Hs
		436286 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		950967 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		893966 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		545353 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		900467 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PDE3A_HUMAN (122-1105): 0: 1058: 44.22
+	Hs
		950995 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		PDE3A_HUMAN (122-1105): 0: 1058: 44.22
+	Hs
		894005 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PDE3A_HUMAN (122-1105): 0: 1058: 44.22
+	Hs
		545375 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		PDE3A_HUMAN (122-1105): 0: 1058: 44.22
+	Hs
		238058 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PDE8A_HUMAN (628-1039): 1.51e-122: 398: 25.00
+	Hs
		845963 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PDE6C_HUMAN (599-1054): 7.62e-124: 402: 20.99
+	Hs
		238054 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		PDE8A_HUMAN (628-1039): 1.51e-122: 398: 25.00