HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005634 - nucleus GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1187
+	Hs
		900899 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		901065 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		900436 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTPRS_HUMAN (555-1181): 7.32e-124: 423: 20.81
+	Hs
		489936 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTPRF_HUMAN (364-1179): 1.6e-116: 401: 15.88
+	Hs
		489942 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTPRF_HUMAN (364-1179): 1.6e-116: 401: 15.88
+	Hs
		900420 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTPRJ_HUMAN (868-1185): 1.34e-115: 392: 29.25
+	Hs
		925235 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTPRJ_HUMAN (868-1185): 1.34e-115: 392: 29.25
+	Hs
		546995 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		719697 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RADI_HUMAN (18-364): 3.83e-121: 388: 20.68
+	Hs
		547002 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		900931 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33
+	Hs
		573648 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTN1_HUMAN (891-1179): 1.76e-118: 375: 31.85
+	Hs
		573655 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTN1_HUMAN (891-1179): 1.76e-118: 375: 31.85
+	Hs
		900421 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		925236 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		660845 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTPRM_HUMAN (552-1183): 8.48e-71: 262: 14.80
+	Hs
		900493 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTPRK_HUMAN (561-1184): 9.67e-69: 255: 14.87
+	Hs
		617094 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTPRG_HUMAN (289-1185): 4.53e-60: 228: 12.65
+	Hs
		617100 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTPRG_HUMAN (289-1185): 4.53e-60: 228: 12.65
+	Hs
		570514 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTN2_HUMAN (928-1179): 1.43e-38: 151: 35.04