Protein: BTBD2
BTB/POZ domain-containing protein 2

Gene: BTBD2
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9BX70

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0005829 - cytosol
GO:0022008 - neurogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114195

CUL3
Cullin-3

10

20

Small-scale

0.972

High

1416604

BTBD1
BTB/POZ domain-containing protein 1

2

19

High-throughput

0.811

High

1272546

CSN6
COP9 signalosome complex subunit 6

7

13

High-throughput

0.750

High

1370348

CSN5
COP9 signalosome complex subunit 5

6

13

High-throughput

0.735

High

1416615

CSN3
COP9 signalosome complex subunit 3

5

20

High-throughput

0.712

High

958707

CSN2
COP9 signalosome complex subunit 2

4

20

High-throughput

0.691

High

542194

TOP1
DNA topoisomerase 1

2

2

Small-scale

0.633

High

1406121

CSN8
COP9 signalosome complex subunit 8

2

5

High-throughput

0.628

High

1416612

CSN7A
COP9 signalosome complex subunit 7a

2

7

High-throughput

0.628

High

1413191

CSN4
COP9 signalosome complex subunit 4

2

6

High-throughput

0.611

High

1157418

PSMD5
26S proteasome non-ATPase regulatory subunit 5

2

1

High-throughput

0.606

High

1392880

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

6

High-throughput

0.606

High

1094407

CSN1
COP9 signalosome complex subunit 1

2

19

High-throughput

0.601

High

1416613

OSGI1
Oxidative stress-induced growth inhibitor 1

3

1

High-throughput

0.596

High

414546

P53
Cellular tumor antigen p53

1

1

High-throughput

0.582

High

1416606

NGB
Neuroglobin

2

0

High-throughput

0.580

High

666904

CCNC
Cyclin-C

2

1

High-throughput

0.553

High

1336458

PNMA1
Paraneoplastic antigen Ma1

2

2

High-throughput

0.549

High

409061

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.541

High

736927

GBP2
Guanylate-binding protein 2

1

1

High-throughput

0.541

High

900134

FXR1
RNA-binding protein FXR1

1

5

High-throughput

0.541

High

996317

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.541

High

1047859

TLE1
Transducin-like enhancer protein 1

1

4

High-throughput

0.541

High

1105168

U119A
Protein unc-119 homolog A

1

2

High-throughput

0.541

High

1123223

DPYL1
Dihydropyrimidinase-related protein 1

1

2

High-throughput

0.541

High

1416607

BRD7
Bromodomain-containing protein 7

1

4

High-throughput

0.541

High

374895

RASH
GTPase HRas

1

2

High-throughput

0.536

High

1046413

UBXN1
UBX domain-containing protein 1

1

8

High-throughput

0.536

High

1104664

IKZF1
DNA-binding protein Ikaros

1

3

High-throughput

0.536

High

1396037

SCYL1
N-terminal kinase-like protein

1

5

High-throughput

0.536

High

1416605

CSN7B
COP9 signalosome complex subunit 7b

1

7

High-throughput

0.536

High

1416617

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.536

High

1311097

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.518

High

557451

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

1153899

SMAD2
Mothers against decapentaplegic homolog 2

1

4

High-throughput

0.508

High

248416

GDF9
Growth/differentiation factor 9

1

1

High-throughput

0.494

High

1139828

SETB1
Histone-lysine N-methyltransferase SETDB1

1

2

High-throughput

0.494

High

1416614

ERG28
Ergosterol biosynthetic protein 28 homolog

1

1

High-throughput

0.494

High

346683

TTC4
Tetratricopeptide repeat protein 4

1

5

High-throughput

0.489

High

1293599

HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

1

1

High-throughput

0.489

High

1329491

OTU6B
Deubiquitinase OTUD6B

1

2

High-throughput

0.489

High

1360282

CSN9
COP9 signalosome complex subunit 9

1

2

High-throughput

0.489

High

1381920

C102A
Coiled-coil domain-containing protein 102A

1

3

High-throughput

0.489

High

1409931

DDX50
ATP-dependent RNA helicase DDX50

1

1

High-throughput

0.489

High

1416609

RBM12
RNA-binding protein 12

1

2

High-throughput

0.489

High

668019

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.481

High

911085

IMA1
Importin subunit alpha-1

1

4

High-throughput

0.481

High

957501

UBC12
NEDD8-conjugating enzyme Ubc12

1

17

High-throughput

0.479

High

1235512

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1309489

CEP97
Centrosomal protein of 97 kDa

1

7

Small-scale

0.479

High

1340804

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

1391739

AURKB
Aurora kinase B

1

9

High-throughput

0.479

High

1416611

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1416616

ARI1
E3 ubiquitin-protein ligase ARIH1

1

16

High-throughput

0.479

High

1396120

Z512B
Zinc finger protein 512B

1

3

High-throughput

0.464

High

1416608

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

1400129

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

5

High-throughput

0.445

High

1332368

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

1

High-throughput

0.407

High

1335310

FA98A
Protein FAM98A

1

1

High-throughput

0.407

High

1416610

SEP11
Septin-11

1

1

High-throughput

0.407

High

827479

MLH1
DNA mismatch repair protein Mlh1

2

0

High-throughput

0.316

High

1415937

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.316

High

339184

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

High-throughput

0.292

High

636762

PTN
Pleiotrophin

1

0

High-throughput

0.282

High

1029929

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.282

High

1209159

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

1394147

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

1416603

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.282

High

1340059

SVIP
Small VCP/p97-interacting protein

1

0

High-throughput

0.279

Low

1271217

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.265

Low

548594

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.249

Low

1356826

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025