HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1369
+	Hs
		900444 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ROCK1_HUMAN (672-1362): 3.23e-31: 135: 11.70
+	Hs
		925253 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ROCK1_HUMAN (672-1362): 3.23e-31: 135: 11.70
+	Hs
		436290 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ROCK1_HUMAN (672-1362): 3.23e-31: 135: 11.70
+	Hs
		950974 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ROCK1_HUMAN (672-1362): 3.23e-31: 135: 11.70
+	Hs
		254464 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		901094 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MRCKB_HUMAN (1175-1367): 5.39e-15: 82.9: 8.70
+	Hs
		725138 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYH10_HUMAN (928-1347): 4.52e-17: 89.6: 16.17
+	Rn
		92842 RHOA_RAT (1-193): 4.1e-81: 240: 99.48		CTRO_RAT (895-1290): 4.85e-14: 80: 13.40
+	Hs
		254468 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		925766 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MRCKB_HUMAN (1175-1367): 5.39e-15: 82.9: 8.70
+	Mm
		823539 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		CTRO_MOUSE (895-1290): 7.4e-14: 79.2: 13.40
+	Mm
		823530 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CTRO_MOUSE (895-1290): 7.4e-14: 79.2: 13.40
+	Hs
		254433 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		254472 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		951494 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MRCKB_HUMAN (1175-1367): 5.39e-15: 82.9: 8.70
+	Hs
		724757 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Hs
		900570 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MRCKA_HUMAN (1190-1369): 6.05e-11: 69.5: 13.98
+	Hs
		925344 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MRCKA_HUMAN (1190-1369): 6.05e-11: 69.5: 13.98
+	Hs
		724776 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Hs
		951069 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MRCKA_HUMAN (1190-1369): 6.05e-11: 69.5: 13.98