HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: LYRIC (Q86UE4)
Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein)
Gene: MTDH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0006357 - regulation of transcription by RNA polymerase II GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 582
+	Hs
		436380 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		951122 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		894172 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		545472 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		892459 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		120512 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		LYRIC_HUMAN (1-582): 0: 949: 100.00