HitPredict

Interactor 1: UBE2N (P61089)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: RNF41 (Q8BH75)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19483718
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Mm			1 317
+	Mm
		895982 UB2D1_MOUSE (4-149): 3.22e-80: 235: 45.21		RNF41_MOUSE (1-317): 7.95e-90: 272: 100.00
+	Hs
		1318719 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM5_HUMAN (11-298): 1.5e-56: 192: 19.19
+	Hs
		1285831 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI43_HUMAN (6-294): 6e-55: 186: 14.73
+	Hs
		135045 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI38_HUMAN (3-295): 3.42e-52: 180: 16.56
+	Hs
		135012 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI38_HUMAN (3-295): 3.42e-52: 180: 16.56
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (9-271): 2.23e-49: 173: 16.54
+	Hs
		1354526 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI10_HUMAN (3-279): 5.06e-49: 171: 16.84
+	Hs
		537142 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75
+	Hs
		1377469 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI17_HUMAN (3-279): 8.91e-44: 157: 12.11
+	Hs
		1356055 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM1_HUMAN (2-299): 7.77e-40: 150: 16.57
+	Hs
		262201 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM3_HUMAN (16-284): 1.77e-39: 149: 14.63
+	Hs
		1318532 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI31_HUMAN (3-275): 1.27e-40: 148: 17.69
+	Hs
		262161 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRIM3_HUMAN (16-284): 1.77e-39: 149: 14.63
+	Hs
		1204911 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI50_HUMAN (3-208): 1.87e-33: 129: 16.27
+	Hs
		1377466 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		1252560 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		LNX1_HUMAN (8-121): 1.33e-26: 111: 27.27
+	Hs
		1163056 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRAF7_HUMAN (8-137): 1.59e-23: 102: 21.77
+	Hs
		1261313 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN138_HUMAN (1-108): 1.78e-24: 100: 23.42
+	Hs
		1283434 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN166_HUMAN (9-118): 8.54e-24: 99.1: 23.42
+	Hs
		1377468 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN114_HUMAN (16-107): 5.06e-09: 57.8: 31.18