HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: EHBP1 (Q8NDI1)
EH domain-binding protein 1
Gene: EHBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0005768 - endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1231
+	Hs
		925443 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EHBP1_HUMAN (1-1231): 0: 651: 100.00
+	Hs
		900570 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MRCKA_HUMAN (542-1224): 3.57e-81: 295: 16.02
+	Hs
		925344 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MRCKA_HUMAN (542-1224): 3.57e-81: 295: 16.02
+	Hs
		164593 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SPTN2_HUMAN (309-1230): 2.21e-69: 259: 14.09
+	Hs
		164599 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SPTN2_HUMAN (309-1230): 2.21e-69: 259: 14.09
+	Hs
		900386 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SPTB2_HUMAN (440-1228): 6.16e-69: 257: 13.85
+	Hs
		925201 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SPTB2_HUMAN (440-1228): 6.16e-69: 257: 13.85
+	Hs
		809093 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		UTRN_HUMAN (307-1230): 1.04e-67: 254: 13.25
+	Hs
		164556 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		SPTN2_HUMAN (309-1230): 2.21e-69: 259: 14.09
+	Hs
		809099 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		UTRN_HUMAN (307-1230): 1.04e-67: 254: 13.25
+	Hs
		164602 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		SPTN2_HUMAN (309-1230): 2.21e-69: 259: 14.09
+	Hs
		436258 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		SPTB2_HUMAN (440-1228): 6.16e-69: 257: 13.85
+	Hs
		436196 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		UTRN_HUMAN (307-1230): 1.04e-67: 254: 13.25
+	Hs
		925432 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EH1L1_HUMAN (992-1224): 1.56e-17: 91: 48.07
+	Hs
		900556 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		CYTSB_HUMAN (399-547): 1.37e-13: 77.8: 36.31
+	Hs
		925335 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CYTSB_HUMAN (399-547): 1.37e-13: 77.8: 36.31
+	Hs
		925387 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MICA3_HUMAN (1029-1214): 2.92e-12: 73.9: 32.46
+	Hs
		436347 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		CYTSB_HUMAN (399-547): 1.37e-13: 77.8: 36.31
+	Hs
		900682 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MILK1_HUMAN (1076-1218): 3.08e-11: 70.1: 32.87
+	Hs
		925433 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MILK1_HUMAN (1076-1218): 3.08e-11: 70.1: 32.87