Protein: NXN
Nucleoredoxin (EC 1.8.1.8)

Gene: NXN
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q6DKJ4

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016055 - Wnt signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

159699

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

5

High-throughput

0.650

High

1231734

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

5

High-throughput

0.628

High

241989

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1231747

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

159364

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

5

High-throughput

0.515

High

208855

ZBT24
Zinc finger and BTB domain-containing protein 24

1

0

High-throughput

0.513

High

185772

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

315688

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

487427

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

588919

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

965020

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

1095032

DUS4
Dual specificity protein phosphatase 4

1

0

High-throughput

0.458

High

1193535

CRY2
Cryptochrome-2

1

0

High-throughput

0.458

High

1231727

U17L2
Ubiquitin carboxyl-terminal hydrolase 17

1

0

Small-scale

0.458

High

1231728

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1231730

ABI1
Abl interactor 1

1

0

High-throughput

0.458

High

1231732

WASF1
Actin-binding protein WASF1

1

0

High-throughput

0.458

High

1231733

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.458

High

1231735

SACA9
Sperm acrosome-associated protein 9

1

0

High-throughput

0.458

High

1231736

CHMP6
Charged multivesicular body protein 6

1

0

High-throughput

0.458

High

1231738

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

1231744

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.458

High

1231746

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.458

High

1226863

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.445

High

330199

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.426

High

1209245

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1231737

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1231731

ARRD1
Arrestin domain-containing protein 1

2

0

High-throughput

0.318

High

1231726

CGB2
Choriogonadotropin subunit beta variant 2

2

0

High-throughput

0.288

High

1231740

GORS1
Golgi reassembly-stacking protein 1

1

0

High-throughput

0.279

Low

1231741

CAD23
Cadherin-23

1

0

High-throughput

0.279

Low

1231743

ANKE1
Ankyrin repeat and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

768423

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1231729

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1231739

GA2L1
GAS2-like protein 1

1

0

High-throughput

0.249

Low

1231742

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1231745

SEC63
Translocation protein SEC63 homolog

1

0

Small-scale

0.238

Low

1103988

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025