HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: LRC59 (Q96AG4)
Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34) [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]
Gene: LRRC59

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 307
+	Hs
		925506 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		LRC59_HUMAN (1-307): 2.82e-54: 180: 100.00
+	Hs
		436449 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		LRC59_HUMAN (1-307): 2.82e-54: 180: 100.00
+	Hs
		951218 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		LRC59_HUMAN (1-307): 2.82e-54: 180: 100.00
+	Hs
		894294 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		LRC59_HUMAN (1-307): 2.82e-54: 180: 100.00
+	Hs
		545551 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		LRC59_HUMAN (1-307): 2.82e-54: 180: 100.00
+	Hs
		900463 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		925273 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		436297 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		950989 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		893999 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		545370 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		900824 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		925539 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		436472 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		951251 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		894337 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		545571 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Dm
		776889 RAC1_DROME (1-193): 2.11e-77: 231: 54.12		SCRIB_DROME (96-224): 1.38e-13: 73.3: 12.40
+	Hs
		925299 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RSU1_HUMAN (9-84): 6.37e-12: 66.6: 34.21
+	Dm
		776906 RAC1_DROME (1-193): 2.11e-77: 231: 54.12		Q9V428_DROME (27-120): 1.69e-09: 59.7: 42.71