Protein: O61444
mitogen-activated protein kinase kinase (EC 2.7.12.2)

Gene: O61444, Mkk4
Organism: Drosophila melanogaster
Interactions: 15
UniProt ID: O61444

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
GO:0007254 - JNK cascade

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

263553

JNK
Stress-activated protein kinase JNK

3

20

Small-scale

0.796

High

197200

RAB6
Ras-related protein Rab6

2

9

High-throughput

0.709

High

55053

A1Z921
Frazzled, isoform B

1

3

Small-scale

0.618

High

263555

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

17

High-throughput

0.618

High

263556

AKT1
RAC serine/threonine-protein kinase

1

16

High-throughput

0.618

High

263558

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

20

Small-scale

0.618

High

263559

MOC2B
Molybdopterin synthase catalytic subunit

1

2

Small-scale

0.489

High

263557

Q8MLW7
X-box-binding protein 1

1

6

High-throughput

0.464

High

263551

PYR1
Multifunctional protein r

1

10

High-throughput

0.445

High

263554

SIMA
Protein similar

1

18

High-throughput

0.437

High

263552

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.407

High

263560

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

14

High-throughput

0.407

High

263562

PNCB
Nicotinate phosphoribosyltransferase

1

1

High-throughput

0.407

High

263561

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

263563

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025