HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RHG39 (Q9C0H5)
Rho GTPase-activating protein 39
Gene: ARHGAP39

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1083
+	Hs
		900443 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9B_HUMAN (273-1074): 7.96e-118: 403: 17.70
+	Hs
		70663 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9A_HUMAN (218-1074): 1.62e-116: 400: 16.31
+	Hs
		901000 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG23_HUMAN (234-1081): 1.44e-107: 370: 15.58
+	Hs
		900564 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG21_HUMAN (324-1081): 4.78e-91: 323: 16.48
+	Sc
		419696 RHO1_YEAST (3-188): 1.51e-97: 283: 73.12		RGA1_YEAST (371-1077): 6.55e-65: 240: 14.32
+	Mm
		925802 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CHIO_MOUSE (774-1078): 2.25e-75: 253: 15.54
+	Hs
		551044 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CHIN_HUMAN (781-1078): 5.84e-73: 251: 17.87
+	Hs
		900637 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SRGP1_HUMAN (644-1080): 9.6e-68: 249: 17.44
+	Hs
		200213 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SRGP3_HUMAN (644-1081): 1.4e-67: 249: 16.48
+	Hs
		856140 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CHIO_HUMAN (767-1078): 4.78e-71: 246: 16.57
+	Mm
		1265268 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		SRGP1_MOUSE (644-1080): 3.18e-63: 236: 16.67
+	Mm
		1125742 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RHG01_MOUSE (759-1079): 7.8e-64: 225: 20.47
+	Hs
		900412 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG01_HUMAN (759-1081): 4.93e-64: 226: 20.64
+	Hs
		925227 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG01_HUMAN (759-1081): 4.93e-64: 226: 20.64
+	Mm
		925791 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG01_MOUSE (759-1079): 7.8e-64: 225: 20.47
+	Hs
		900634 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG22_HUMAN (871-1082): 4.33e-55: 206: 31.98
+	Mm
		925805 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG22_MOUSE (871-1083): 1.07e-54: 205: 31.84
+	Hs
		925314 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG44_HUMAN (872-1082): 8.45e-51: 195: 27.15
+	Hs
		900426 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ABR_HUMAN (886-1080): 1.48e-33: 141: 23.01
+	Mm
		925793 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		ABR_MOUSE (886-1080): 1.55e-33: 141: 23.01