HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ARFG3 (Q9NP61)
ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)
Gene: ARFGAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 516
+	Hs
		951367 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00
+	Hs
		894467 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00
+	Hs
		951154 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ARFG2_HUMAN (2-516): 4.95e-137: 407: 53.61
+	Hs
		894214 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ARFG2_HUMAN (2-516): 4.95e-137: 407: 53.61
+	Hs
		925751 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15
+	Gg
		1154344 Q6LC82_CHICK (1-193): 8.86e-80: 237: 57.22		Q9DG15_CHICK (17-419): 6.11e-72: 244: 14.88
+	Hs
		951478 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15
+	Hs
		894610 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15
+	Hs
		545710 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15
+	Hs
		925724 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ASAP1_HUMAN (2-459): 1.98e-65: 231: 15.53
+	Hs
		925274 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		GIT2_HUMAN (17-418): 2.96e-62: 219: 14.50
+	Hs
		892677 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		ASAP1_HUMAN (2-459): 1.98e-65: 231: 15.53
+	Hs
		950990 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		GIT2_HUMAN (17-418): 2.96e-62: 219: 14.50
+	Hs
		894000 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		GIT2_HUMAN (17-418): 2.96e-62: 219: 14.50
+	Hs
		545371 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		GIT2_HUMAN (17-418): 2.96e-62: 219: 14.50
+	Hs
		892368 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		GIT2_HUMAN (17-418): 2.96e-62: 219: 14.50
+	Hs
		900732 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SMAP2_HUMAN (10-165): 2.4e-44: 163: 30.46
+	Hs
		901056 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		AGAP1_HUMAN (5-114): 2.74e-35: 142: 34.55
+	Hs
		925736 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		AGAP1_HUMAN (5-114): 2.74e-35: 142: 34.55
+	Hs
		894593 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		AGAP1_HUMAN (5-114): 2.74e-35: 142: 34.55