HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: L2GL1 (Q15334)
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)
Gene: LLGL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 244 Hs			1 1064
+	Hs
		852487 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		436316 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		1071550 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		915693 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		894033 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		925296 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		545393 RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		900495 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		892387 RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		951010 RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		120451 RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		1071576 RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		564540 RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		925363 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		L2GL2_HUMAN (5-979): 0: 1216: 56.97
+	Hs
		925342 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		STXB5_HUMAN (14-1064): 0: 1055: 25.47
+	Hs
		900563 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		STXB5_HUMAN (14-1064): 0: 1055: 25.47
+	Hs
		951061 RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47		STXB5_HUMAN (14-1064): 0: 1055: 25.47