Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: ARL8B (Q9NVJ2)
ADP-ribosylation factor-like protein 8B (EC 3.6.5.2) (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)
Gene: ARL8B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 29360040, 28325809, 35271311, 40437099
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
and 6 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 207
Hs

1 186
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Zm
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025