HitPredict

Interactor 1: H3 (P61830)
Histone H3
Gene: HHT1

Interactor 2: SPP1 (Q03012)
COMPASS component SPP1 (Complex proteins associated with SET1 protein SPP1) (Set1C component SPP1) (Suppressor of PRP protein 1)
Gene: SPP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.725

Property	Details
Experiments	30325428, 17142463, 17898715, 31253666, 19270702, 20347846
Identification Methods	unspecified method, affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Sc			1 353
+	Hs
		935373 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Hs
		952701 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Hs
		935185 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		952594 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		1086300 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		DIDO1_HUMAN (8-149): 5.54e-32: 129: 19.46
+	Hs
		256400 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Hs
		256401 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Hs
		256412 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Mm
		93660 H33_MOUSE (1-136): 1.25e-61: 187: 90.44		E9Q6A7_MOUSE (11-126): 7.8e-23: 102: 23.08
+	Hs
		934702 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		952300 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		1017307 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		935055 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		PHF3_HUMAN (24-156): 4.18e-21: 96.8: 18.31
+	Hs
		952509 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		PHF3_HUMAN (24-156): 4.18e-21: 96.8: 18.31
+	Hs
		1086245 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		PHF3_HUMAN (24-156): 4.18e-21: 96.8: 18.31
+	Hs
		935370 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		952699 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		934868 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		952396 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		1086177 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86