HitPredict

Interactor 1: H3 (P61830)
Histone H3
Gene: HHT1

Interactor 2: SWR1 (Q05471)
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1)
Gene: SWR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	30309918, 21179020
Identification Methods	pull down, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Sc			1 1514
+	Mm
		935460 H31_MOUSE (1-136): 3.24e-62: 188: 88.97		SMCA5_MOUSE (1033-1509): 2.11e-85: 305: 24.69
+	Hs
		229359 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69
+	Hs
		935016 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		CHD5_HUMAN (1002-1506): 4.73e-83: 304: 23.09
+	Mm
		952763 H33_MOUSE (1-136): 1.25e-61: 187: 90.44		SMCA5_MOUSE (1033-1509): 2.11e-85: 305: 24.69
+	Hs
		229363 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69
+	Hs
		935324 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		CHD7_HUMAN (1114-1509): 6.46e-82: 301: 26.38
+	Hs
		952670 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		CHD7_HUMAN (1114-1509): 6.46e-82: 301: 26.38
+	Hs
		934705 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		CHD3_HUMAN (1017-1463): 2.27e-80: 296: 24.89
+	Hs
		935262 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		CHD8_HUMAN (1034-1508): 5.26e-80: 295: 23.70
+	Hs
		952302 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		CHD3_HUMAN (1017-1463): 2.27e-80: 296: 24.89
+	Hs
		952639 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		CHD8_HUMAN (1034-1508): 5.26e-80: 295: 23.70
+	Hs
		935014 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		CHD6_HUMAN (1034-1507): 1.98e-79: 293: 23.54
+	Hs
		952373 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		CHD9_HUMAN (1108-1510): 5.26e-78: 288: 26.18
+	Hs
		658647 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		SMCA1_HUMAN (1060-1503): 5.31e-78: 283: 26.51
+	Hs
		658651 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		SMCA1_HUMAN (1060-1503): 5.31e-78: 283: 26.51
+	Hs
		846743 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		SMCA2_HUMAN (1090-1484): 4.11e-73: 272: 23.89
+	Hs
		846921 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		SMCA4_HUMAN (1036-1496): 9.82e-72: 267: 19.60
+	Hs
		846925 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		SMCA4_HUMAN (1036-1496): 9.82e-72: 267: 19.60
+	Hs
		934908 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		SRCAP_HUMAN (282-660): 5.08e-44: 178: 14.17
+	Hs
		952426 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		SRCAP_HUMAN (282-660): 5.08e-44: 178: 14.17