Interactor 1: SCNNB (P51168)
Epithelial sodium channel subunit beta (Beta-ENaC) (ENaC subunit beta) (ENaCB) (Epithelial Na(+) channel subunit beta) (Amiloride-sensitive sodium channel subunit beta) (Beta-NaCH) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB)
Gene: SCNN1B

Interactor 2: SCNNG (P51170)
Epithelial sodium channel subunit gamma (ENaC subunit gamma) (ENaCG) (Epithelial Na(+) channel subunit gamma) (Gamma-ENaC) (Amiloride-sensitive sodium channel subunit gamma) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Sodium channel epithelial 1 subunit gamma)
Gene: SCNN1G

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 22526458
Identification Methods protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ASC~ASC
Common GO terms GO:0005886 - plasma membrane
GO:0006883 - intracellular sodium ion homeostasis
GO:0008217 - regulation of blood pressure
GO:0009897 - external side of plasma membrane
GO:0015280 - ligand-gated sodium channel activity
and 13 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 640
Hs

1 649
+ Rn
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+ Rn
+ Hs
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+ Gg

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Last updated: 11Aug2025