Protein: ASIC4
Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary)

Gene: ASIC4
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q96FT7

Gene Ontology (top 5):
GO:0001662 - behavioral fear response
GO:0005886 - plasma membrane
GO:0015280 - ligand-gated sodium channel activity
GO:0035725 - sodium ion transmembrane transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580815

PVR
Poliovirus receptor

1

3

High-throughput

0.691

High

788539

SCNNA
Epithelial sodium channel subunit alpha

1

12

High-throughput

0.691

High

1006027

ASIC1
Acid-sensing ion channel 1

1

13

High-throughput

0.691

High

1293281

LSR
Lipolysis-stimulated lipoprotein receptor

3

0

High-throughput

0.634

High

1309796

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

3

0

High-throughput

0.634

High

222389

TSN6
Tetraspanin-6

2

1

High-throughput

0.628

High

354161

CLPT1
Putative lipid scramblase CLPTM1

2

2

High-throughput

0.628

High

520962

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

8

High-throughput

0.628

High

870829

GLRB
Glycine receptor subunit beta

2

1

High-throughput

0.628

High

1081641

HSP7E
Heat shock 70 kDa protein 14

2

1

High-throughput

0.628

High

1390867

ABCA3
Phospholipid-transporting ATPase ABCA3

2

1

High-throughput

0.628

High

1390888

CNNM1
Metal transporter CNNM1

2

3

High-throughput

0.628

High

1390907

LRP12
Low-density lipoprotein receptor-related protein 12

2

2

High-throughput

0.628

High

1339791

CADM4
Cell adhesion molecule 4

1

2

High-throughput

0.618

High

1390891

UFSP2
Ufm1-specific protease 2

3

1

High-throughput

0.604

High

1390900

FBX2
F-box only protein 2

3

1

High-throughput

0.604

High

243820

ADCY3
Adenylate cyclase type 3

2

0

High-throughput

0.602

High

1390874

SGPP1
Sphingosine-1-phosphate phosphatase 1

2

0

High-throughput

0.602

High

1390882

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.602

High

1390886

PGAP6
Post-GPI attachment to proteins factor 6

2

0

High-throughput

0.602

High

1335214

NETO2
Neuropilin and tolloid-like protein 2

2

1

High-throughput

0.574

High

1390869

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

2

2

High-throughput

0.574

High

1390881

ALG9
Alpha-1,2-mannosyltransferase ALG9

2

2

High-throughput

0.574

High

1390896

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

6

High-throughput

0.574

High

1390902

POMT2
Protein O-mannosyl-transferase 2

2

3

High-throughput

0.574

High

380118

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

8

High-throughput

0.552

High

1211184

ODR4
Protein odr-4 homolog

2

1

High-throughput

0.549

High

1252822

NFXL1
NF-X1-type zinc finger protein NFXL1

2

2

High-throughput

0.549

High

1390877

LMA2L
VIP36-like protein

2

1

High-throughput

0.549

High

1390887

AT131
Endoplasmic reticulum transmembrane helix translocase

2

1

High-throughput

0.549

High

161073

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.536

High

175411

PLXB2
Plexin-B2

1

4

High-throughput

0.536

High

277035

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

2

High-throughput

0.536

High

380650

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

14

High-throughput

0.536

High

409470

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

8

High-throughput

0.536

High

472114

MET
Hepatocyte growth factor receptor

1

4

High-throughput

0.536

High

603802

ITA2
Integrin alpha-2

1

2

High-throughput

0.536

High

655000

ITA6
Integrin alpha-6

1

2

High-throughput

0.536

High

703436

GBRB3
Gamma-aminobutyric acid receptor subunit beta-3

1

1

High-throughput

0.536

High

719735

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

8

High-throughput

0.536

High

720014

HMOX2
Heme oxygenase 2

1

1

High-throughput

0.536

High

907931

PLXA3
Plexin-A3

1

4

High-throughput

0.536

High

1009161

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

17

High-throughput

0.536

High

1034317

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

2

High-throughput

0.536

High

1049188

RON
Macrophage-stimulating protein receptor

1

4

High-throughput

0.536

High

1116735

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

2

High-throughput

0.536

High

1143771

PON2
Serum paraoxonase/arylesterase 2

1

5

High-throughput

0.536

High

1180951

HFE
Hereditary hemochromatosis protein

1

9

High-throughput

0.536

High

1337048

CNNM3
Metal transporter CNNM3

1

3

High-throughput

0.536

High

1376958

HMR1
Major histocompatibility complex class I-related protein 1

1

9

High-throughput

0.536

High

1390875

CNTP3
Contactin-associated protein-like 3

1

2

High-throughput

0.536

High

1390879

SEM6B
Semaphorin-6B

1

1

High-throughput

0.536

High

1390883

CNNM2
Metal transporter CNNM2

1

3

High-throughput

0.536

High

1390889

SEM4G
Semaphorin-4G

1

2

High-throughput

0.536

High

1390890

T106B
Transmembrane protein 106B

1

2

High-throughput

0.536

High

1390903

JAG2
Protein jagged-2

1

1

High-throughput

0.536

High

1390908

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

2

High-throughput

0.536

High

1390909

ST14
Suppressor of tumorigenicity 14 protein

1

1

High-throughput

0.536

High

564201

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

927099

ATX3
Ataxin-3

1

1

High-throughput

0.515

High

61130

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.513

High

571246

PERF
Perforin-1

1

0

High-throughput

0.513

High

612107

ITB5
Integrin beta-5

1

0

High-throughput

0.513

High

834685

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

934262

BI1
Bax inhibitor 1

1

0

High-throughput

0.513

High

1032639

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.513

High

1089121

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.513

High

1175826

T132A
Transmembrane protein 132A

1

0

High-throughput

0.513

High

1213211

AGRF1
Adhesion G-protein coupled receptor F1

1

0

High-throughput

0.513

High

1228235

HGNAT
Heparan-alpha-glucosaminide N-acetyltransferase

1

0

High-throughput

0.513

High

1339605

NLGN2
Neuroligin-2

1

0

High-throughput

0.513

High

1356102

SCRB1
Scavenger receptor class B member 1

1

0

High-throughput

0.513

High

1366829

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

0

High-throughput

0.513

High

1390892

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.513

High

1390899

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.513

High

442436

GELS
Gelsolin

1

0

High-throughput

0.493

High

650351

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.493

High

705506

GRN
Progranulin

1

0

High-throughput

0.493

High

713127

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.493

High

896853

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

931056

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

1133907

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.493

High

1279688

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

193717

TPSN
Tapasin

1

2

High-throughput

0.489

High

324027

CSTN1
Calsyntenin-1

1

2

High-throughput

0.489

High

992299

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.489

High

1022449

IDD
Integral membrane protein DGCR2/IDD

1

1

High-throughput

0.489

High

1143828

PON3
Serum paraoxonase/lactonase 3

1

5

High-throughput

0.489

High

1312531

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

1

High-throughput

0.489

High

1390801

GLT14
Polypeptide N-acetylgalactosaminyltransferase 14

1

1

High-throughput

0.489

High

1390859

TECT2
Tectonic-2

1

2

High-throughput

0.489

High

1390868

CSTN3
Calsyntenin-3

1

2

High-throughput

0.489

High

1390872

T106C
Transmembrane protein 106C

1

2

High-throughput

0.489

High

1390893

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.489

High

1390895

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

1390904

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.489

High

246089

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.470

High

1390906

RNF11
RING finger protein 11

1

1

High-throughput

0.470

High

380574

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

12

High-throughput

0.445

High

1090000

LMAN2
Vesicular integral-membrane protein VIP36

1

1

High-throughput

0.445

High

1390862

KIRR1
Kin of IRRE-like protein 1

1

2

High-throughput

0.445

High

787439

TGFR1
TGF-beta receptor type-1

1

0

High-throughput

0.426

High

1381449

PMEPA
Protein TMEPAI

1

0

High-throughput

0.426

High

1390910

ROBO1
Roundabout homolog 1

1

0

High-throughput

0.426

High

170916

CLGN
Calmegin

1

2

High-throughput

0.407

High

1126042

GAS6
Growth arrest-specific protein 6

1

1

High-throughput

0.407

High

1390865

CNT3B
Contactin-associated protein-like 3B

1

2

High-throughput

0.407

High

1362074

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

3

0

High-throughput

0.345

High

72673

UPK3L
Uroplakin-3b-like protein 1

2

0

High-throughput

0.328

High

219822

CHSTA
Carbohydrate sulfotransferase 10

2

0

High-throughput

0.328

High

1214118

DIK1A
Divergent protein kinase domain 1A

2

0

High-throughput

0.328

High

1217318

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

2

0

High-throughput

0.328

High

1309646

GLBL2
Beta-galactosidase-1-like protein 2

2

0

High-throughput

0.328

High

1327926

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.328

High

1372363

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

2

0

High-throughput

0.328

High

1390858

BSCL2
Seipin

2

0

High-throughput

0.328

High

1390861

TXD15
Thioredoxin domain-containing protein 15

2

0

High-throughput

0.328

High

1390876

OSBL8
Oxysterol-binding protein-related protein 8

2

0

High-throughput

0.328

High

1390880

TM231
Transmembrane protein 231

2

0

High-throughput

0.328

High

1390905

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.328

High

282615

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

2

0

High-throughput

0.324

High

733265

OTX2
Homeobox protein OTX2

2

0

High-throughput

0.316

High

1390860

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

2

0

High-throughput

0.313

High

1390898

SE1L1
Protein sel-1 homolog 1

2

0

High-throughput

0.313

High

1307604

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

397751

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

High-throughput

0.279

Low

858697

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

0

High-throughput

0.279

Low

885499

MA2A2
Alpha-mannosidase 2x

1

0

High-throughput

0.279

Low

1143659

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1204889

MKS3
Meckelin

1

0

High-throughput

0.279

Low

1225408

METRL
Meteorin-like protein

1

0

High-throughput

0.279

Low

1242409

OFUT3
GDP-fucose protein O-fucosyltransferase 3

1

0

High-throughput

0.279

Low

1254303

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.279

Low

1288098

OAF
Out at first protein homolog

1

0

High-throughput

0.279

Low

1293495

COMD2
COMM domain-containing protein 2

1

0

High-throughput

0.279

Low

1315219

TRM44
Probable tRNA

1

0

High-throughput

0.279

Low

1337631

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.279

Low

1347136

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.279

Low

1356807

NEUFC
Neuferricin

1

0

High-throughput

0.279

Low

1380518

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

1382141

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.279

Low

1388079

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

1390864

F210A
Protein FAM210A

1

0

High-throughput

0.279

Low

1390866

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

0

High-throughput

0.279

Low

1390870

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.279

Low

1390873

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.279

Low

1390885

TPC
Mitochondrial thiamine pyrophosphate carrier

1

0

High-throughput

0.279

Low

1390894

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.279

Low

1390897

COMD3
COMM domain-containing protein 3

1

0

High-throughput

0.279

Low

47395

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

159999

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

160745

TOR1A
Torsin-1A

1

0

High-throughput

0.268

Low

165777

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

High-throughput

0.268

Low

167353

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

216779

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.268

Low

301625

WFS1
Wolframin

1

0

High-throughput

0.268

Low

415779

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.268

Low

570551

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.268

Low

622244

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

832101

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.268

Low

843860

HD
Huntingtin

1

0

High-throughput

0.268

Low

856863

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.268

Low

884780

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.268

Low

927481

ATX1
Ataxin-1

1

0

High-throughput

0.268

Low

954575

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1081557

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

1096159

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.268

Low

1369608

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.268

Low

1390871

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1390884

Q9HAV2
Heat shock transcription factor 1

1

0

High-throughput

0.249

Low

361713

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.232

Low

1140230

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.232

Low

1233999

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

1

0

High-throughput

0.232

Low

1390863

SRAC1
Protein SERAC1

1

0

High-throughput

0.232

Low

1390878

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.232

Low

1390901

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025