Protein: ASXL3
Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3)

Gene: ASXL3
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9C0F0

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0009887 - animal organ morphogenesis
GO:0035517 - PR-DUB complex
GO:0042975 - peroxisome proliferator activated receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1267150

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

3

10

Small-scale

0.847

High

244907

BRD4
Bromodomain-containing protein 4

2

10

Small-scale

0.595

High

508703

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.515

High

851675

NEK4
Serine/threonine-protein kinase Nek4

1

8

High-throughput

0.489

High

175184

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

Small-scale

0.479

High

183157

KDM6A
Lysine-specific demethylase 6A

1

9

Small-scale

0.479

High

215030

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

High-throughput

0.479

High

241633

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.479

High

243594

DNJA2
DnaJ homolog subfamily A member 2

1

16

High-throughput

0.479

High

311619

SMC2
Structural maintenance of chromosomes protein 2

1

4

High-throughput

0.479

High

363900

ALBU
Albumin

1

4

High-throughput

0.479

High

377662

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

396985

HMGN1
Non-histone chromosomal protein HMG-14

1

1

High-throughput

0.479

High

398945

HMGN2
Non-histone chromosomal protein HMG-17

1

5

High-throughput

0.479

High

415054

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.479

High

428416

TBB5
Tubulin beta chain

1

8

High-throughput

0.479

High

428701

TRY1
Serine protease 1

1

5

High-throughput

0.479

High

453596

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

13

High-throughput

0.479

High

502526

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.479

High

518760

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

4

High-throughput

0.479

High

523991

XRCC6
X-ray repair cross-complementing protein 6

1

7

High-throughput

0.479

High

538022

KPYM
Pyruvate kinase PKM

1

2

High-throughput

0.479

High

543069

GLNA
Glutamine synthetase

1

3

High-throughput

0.479

High

582482

NUCL
Nucleolin

1

10

High-throughput

0.479

High

607715

NDKB
Nucleoside diphosphate kinase B

1

5

High-throughput

0.479

High

616508

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

658155

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

2

High-throughput

0.479

High

669464

EF1D
Elongation factor 1-delta

1

6

High-throughput

0.479

High

681586

DNJA1
DnaJ homolog subfamily A member 1

1

16

High-throughput

0.479

High

724014

CBS
Cystathionine beta-synthase

1

2

High-throughput

0.479

High

745294

RBMX
RNA-binding motif protein, X chromosome

1

10

High-throughput

0.479

High

835239

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

1

High-throughput

0.479

High

848287

HCFC1
Host cell factor 1

1

4

Small-scale

0.479

High

857508

HMGA2
High mobility group protein HMGI-C

1

4

High-throughput

0.479

High

896817

ARP3
Actin-related protein 3

1

15

High-throughput

0.479

High

917885

H4
Histone H4

1

8

High-throughput

0.479

High

919259

RAN
GTP-binding nuclear protein Ran

1

11

High-throughput

0.479

High

930985

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

9

High-throughput

0.479

High

931396

YBOX1
Y-box-binding protein 1

1

5

High-throughput

0.479

High

933962

TBB4B
Tubulin beta-4B chain

1

8

High-throughput

0.479

High

936015

HBG1
Hemoglobin subunit gamma-1

1

6

High-throughput

0.479

High

962349

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

14

High-throughput

0.479

High

964248

FOXK2
Forkhead box protein K2

1

8

Small-scale

0.479

High

1019629

ILF2
Interleukin enhancer-binding factor 2

1

3

High-throughput

0.479

High

1072004

PCBP1
Poly(rC)-binding protein 1

1

15

High-throughput

0.479

High

1082378

DDB1
DNA damage-binding protein 1

1

7

High-throughput

0.479

High

1216329

RIOX2
Ribosomal oxygenase 2

1

1

High-throughput

0.479

High

1243841

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

Small-scale

0.479

High

1266119

DDX1
ATP-dependent RNA helicase DDX1

1

10

High-throughput

0.479

High

1288481

MBD6
Methyl-CpG-binding domain protein 6

1

16

High-throughput

0.479

High

1304236

PARK7
Parkinson disease protein 7

1

4

High-throughput

0.479

High

1304869

TSNAX
Translin-associated protein X

1

1

High-throughput

0.479

High

1319310

MBD5
Methyl-CpG-binding domain protein 5

1

6

High-throughput

0.479

High

1319315

RTRAF
RNA transcription, translation and transport factor protein

1

2

High-throughput

0.479

High

1319316

RUVB2
RuvB-like 2

1

8

High-throughput

0.479

High

1319319

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

833814

CLK1
Dual specificity protein kinase CLK1

1

18

High-throughput

0.457

High

168971

ARPC2
Actin-related protein 2/3 complex subunit 2

1

2

High-throughput

0.437

High

169129

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.437

High

197395

SERA
D-3-phosphoglycerate dehydrogenase

1

11

High-throughput

0.437

High

211242

BUB3
Mitotic checkpoint protein BUB3

1

14

High-throughput

0.437

High

264623

MTX2
Metaxin-2

1

2

High-throughput

0.437

High

266808

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

1

High-throughput

0.437

High

335625

GSHR
Glutathione reductase, mitochondrial

1

2

High-throughput

0.437

High

337122

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

2

High-throughput

0.437

High

361399

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.437

High

361607

APOA2
Apolipoprotein A-II

1

3

High-throughput

0.437

High

376501

APOB
Apolipoprotein B-100

1

2

High-throughput

0.437

High

380684

K2C1
Keratin, type II cytoskeletal 1

1

2

High-throughput

0.437

High

382139

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.437

High

397499

ADT2
ADP/ATP translocase 2

1

11

High-throughput

0.437

High

415482

ATPB
ATP synthase subunit beta, mitochondrial

1

12

High-throughput

0.437

High

417026

IF4E
Eukaryotic translation initiation factor 4E

1

4

High-throughput

0.437

High

417410

ENOA
Alpha-enolase

1

8

High-throughput

0.437

High

432241

HS90A
Heat shock protein HSP 90-alpha

1

11

High-throughput

0.437

High

438505

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.437

High

469891

CO4A
Complement C4-A

1

4

High-throughput

0.437

High

489261

H14
Histone H1.4

1

14

High-throughput

0.437

High

500093

CH60
60 kDa heat shock protein, mitochondrial

1

8

High-throughput

0.437

High

531417

K1C10
Keratin, type I cytoskeletal 10

1

3

High-throughput

0.437

High

541417

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.437

High

548951

NDKA
Nucleoside diphosphate kinase A

1

5

High-throughput

0.437

High

559928

H12
Histone H1.2

1

14

High-throughput

0.437

High

606483

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

2

High-throughput

0.437

High

617898

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.437

High

637048

ATPA
ATP synthase subunit alpha, mitochondrial

1

12

High-throughput

0.437

High

656879

GSTM2
Glutathione S-transferase Mu 2

1

2

High-throughput

0.437

High

670760

PRDX6
Peroxiredoxin-6

1

10

High-throughput

0.437

High

672287

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

7

High-throughput

0.437

High

678066

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

3

High-throughput

0.437

High

685763

PRDX2
Peroxiredoxin-2

1

10

High-throughput

0.437

High

704282

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

2

High-throughput

0.437

High

722506

RL22
Large ribosomal subunit protein eL22

1

2

High-throughput

0.437

High

724134

K1C9
Keratin, type I cytoskeletal 9

1

1

High-throughput

0.437

High

729170

K22E
Keratin, type II cytoskeletal 2 epidermal

1

5

High-throughput

0.437

High

751815

GRP75
Stress-70 protein, mitochondrial

1

17

High-throughput

0.437

High

759816

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.437

High

778271

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

5

High-throughput

0.437

High

800066

VDAC2
Voltage-dependent anion-selective channel protein 2

1

9

High-throughput

0.437

High

807518

RS10
Small ribosomal subunit protein eS10

1

6

High-throughput

0.437

High

813156

CAZA2
F-actin-capping protein subunit alpha-2

1

7

High-throughput

0.437

High

826056

FAS
Fatty acid synthase

1

3

High-throughput

0.437

High

826871

TCPG
T-complex protein 1 subunit gamma

1

15

High-throughput

0.437

High

827575

EFTU
Elongation factor Tu, mitochondrial

1

13

High-throughput

0.437

High

838681

GDIB
Rab GDP dissociation inhibitor beta

1

5

High-throughput

0.437

High

843035

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.437

High

850186

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

8

High-throughput

0.437

High

853459

IMA1
Importin subunit alpha-1

1

3

High-throughput

0.437

High

857210

CAZA1
F-actin-capping protein subunit alpha-1

1

7

High-throughput

0.437

High

882154

GSC
Homeobox protein goosecoid

1

6

High-throughput

0.437

High

887497

ARPC4
Actin-related protein 2/3 complex subunit 4

1

1

High-throughput

0.437

High

899029

PSME3
Proteasome activator complex subunit 3

1

2

High-throughput

0.437

High

903498

WDR5
WD repeat-containing protein 5

1

11

High-throughput

0.437

High

905733

RS7
Small ribosomal subunit protein eS7

1

3

High-throughput

0.437

High

910926

RS18
Small ribosomal subunit protein uS13

1

2

High-throughput

0.437

High

912376

SMD1
Small nuclear ribonucleoprotein Sm D1

1

5

High-throughput

0.437

High

912558

SMD2
Small nuclear ribonucleoprotein Sm D2

1

2

High-throughput

0.437

High

920550

RS25
Small ribosomal subunit protein eS25

1

1

High-throughput

0.437

High

924405

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

High-throughput

0.437

High

927498

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.437

High

929996

ACTG
Actin, cytoplasmic 2

1

13

High-throughput

0.437

High

932857

EF1A1
Elongation factor 1-alpha 1

1

10

High-throughput

0.437

High

933344

TBA1B
Tubulin alpha-1B chain

1

20

High-throughput

0.437

High

934456

CSK21
Casein kinase II subunit alpha

1

14

High-throughput

0.437

High

936076

HBA
Hemoglobin subunit alpha

1

6

High-throughput

0.437

High

943465

TCPB
T-complex protein 1 subunit beta

1

18

High-throughput

0.437

High

952868

FOXK1
Forkhead box protein K1

1

9

Small-scale

0.437

High

989386

PRDX1
Peroxiredoxin-1

1

10

High-throughput

0.437

High

990293

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

4

High-throughput

0.437

High

997892

RBBP4
Histone-binding protein RBBP4

1

10

High-throughput

0.437

High

1012517

HSP7E
Heat shock 70 kDa protein 14

1

12

High-throughput

0.437

High

1024993

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

3

High-throughput

0.437

High

1060911

IMB1
Importin subunit beta-1

1

9

High-throughput

0.437

High

1072177

PCBP2
Poly(rC)-binding protein 2

1

13

High-throughput

0.437

High

1073143

SF3B3
Splicing factor 3B subunit 3

1

7

High-throughput

0.437

High

1073999

SC23A
Protein transport protein Sec23A

1

2

High-throughput

0.437

High

1074230

SF3A1
Splicing factor 3A subunit 1

1

15

High-throughput

0.437

High

1080976

SEPT7
Septin-7

1

6

High-throughput

0.437

High

1086483

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

2

High-throughput

0.437

High

1087098

H2A2C
Histone H2A type 2-C

1

10

High-throughput

0.437

High

1204089

CARM1
Histone-arginine methyltransferase CARM1

1

8

High-throughput

0.437

High

1274041

CUL5
Cullin-5

1

11

High-throughput

0.437

High

1283767

ISOC2
Isochorismatase domain-containing protein 2

1

4

High-throughput

0.437

High

1286952

ISOC1
Isochorismatase domain-containing protein 1

1

4

High-throughput

0.437

High

1305244

PHB2
Prohibitin-2

1

5

High-throughput

0.437

High

1305815

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.437

High

1306968

ANM1
Protein arginine N-methyltransferase 1

1

8

High-throughput

0.437

High

1310073

TIRR
Tudor-interacting repair regulator protein

1

2

High-throughput

0.437

High

1319305

SKI8
Superkiller complex protein 8

1

13

High-throughput

0.437

High

1319306

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

1

High-throughput

0.437

High

1319307

VP37B
Vacuolar protein sorting-associated protein 37B

1

1

High-throughput

0.437

High

1319308

CYBP
Calcyclin-binding protein

1

3

High-throughput

0.437

High

1319309

RCC2
Protein RCC2

1

5

High-throughput

0.437

High

1319311

HOP2
Homologous-pairing protein 2 homolog

1

2

High-throughput

0.437

High

1319312

PFD2
Prefoldin subunit 2

1

2

High-throughput

0.437

High

1319313

DNPEP
Aspartyl aminopeptidase

1

2

High-throughput

0.437

High

1319314

MCTS1
Malignant T-cell-amplified sequence 1

1

1

High-throughput

0.437

High

1319317

RUVB1
RuvB-like 1

1

8

High-throughput

0.437

High

1319318

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.437

High

136215

SCD
Stearoyl-CoA desaturase

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024