Protein: CERS6
Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)

Gene: CERS6
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q6ZMG9

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006954 - inflammatory response
GO:0014003 - oligodendrocyte development
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1168262

CERS4
Ceramide synthase 4

1

6

High-throughput

0.691

High

1168231

RETR3
Reticulophagy regulator 3

3

1

High-throughput

0.667

High

1168243

LPAR1
Lysophosphatidic acid receptor 1

3

13

High-throughput

0.667

High

1168258

P2Y12
P2Y purinoceptor 12

3

13

High-throughput

0.667

High

1168260

SG196
Protein O-mannose kinase

3

4

High-throughput

0.667

High

1168228

CERS6
Ceramide synthase 6

1

6

Small-scale

0.647

High

1168245

CERS2
Ceramide synthase 2

1

6

Small-scale

0.647

High

626539

FPR2
N-formyl peptide receptor 2

2

19

High-throughput

0.628

High

1083451

C3AR
C3a anaphylatoxin chemotactic receptor

2

20

High-throughput

0.628

High

567858

HXB9
Homeobox protein Hox-B9

1

4

High-throughput

0.618

High

623289

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

2

1

High-throughput

0.611

High

1168265

GPR84
G-protein coupled receptor 84

3

9

High-throughput

0.604

High

781078

OPRX
Nociceptin receptor

2

5

High-throughput

0.591

High

674858

AGTR1
Type-1 angiotensin II receptor

1

15

High-throughput

0.582

High

263266

SC22B
Vesicle-trafficking protein SEC22b

2

0

High-throughput

0.580

High

436927

ACM4
Muscarinic acetylcholine receptor M4

2

10

High-throughput

0.574

High

658250

5HT2C
5-hydroxytryptamine receptor 2C

2

9

High-throughput

0.574

High

783662

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

8

High-throughput

0.574

High

1168251

GPR21
Probable G-protein coupled receptor 21

2

5

High-throughput

0.574

High

1168261

IPPK
Inositol-pentakisphosphate 2-kinase

2

3

High-throughput

0.574

High

1168255

B2L13
Bcl-2-like protein 13

1

1

Small-scale

0.561

High

126017

UPK1A
Uroplakin-1a

1

5

High-throughput

0.536

High

313932

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

415381

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.536

High

591223

ACM3
Muscarinic acetylcholine receptor M3

1

12

High-throughput

0.536

High

654455

CALX
Calnexin

1

2

High-throughput

0.536

High

674042

V2R
Vasopressin V2 receptor

1

8

High-throughput

0.536

High

676563

CTR1
High affinity cationic amino acid transporter 1

1

3

High-throughput

0.536

High

735980

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.536

High

823055

AGRE5
Adhesion G protein-coupled receptor E5

1

4

High-throughput

0.536

High

986091

KDSR
3-ketodihydrosphingosine reductase

1

3

High-throughput

0.536

High

1168235

AGRG5
Adhesion G-protein coupled receptor G5

1

3

High-throughput

0.536

High

1168236

AGRG2
Adhesion G-protein coupled receptor G2

1

3

High-throughput

0.536

High

1168240

SPP2B
Signal peptide peptidase-like 2B

1

1

High-throughput

0.536

High

1168241

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.536

High

1168244

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

2

High-throughput

0.536

High

1168246

BSCL2
Seipin

1

3

High-throughput

0.536

High

1168247

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.536

High

1168250

SEC62
Translocation protein SEC62

1

3

High-throughput

0.536

High

1168252

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

1

High-throughput

0.536

High

1168253

CML1
Chemerin-like receptor 1

1

17

High-throughput

0.536

High

1168259

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.536

High

1168267

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

1

High-throughput

0.536

High

1168273

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

1

High-throughput

0.536

High

213132

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

798504

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

0

High-throughput

0.513

High

864226

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.513

High

886947

T2R19
Taste receptor type 2 member 19

1

0

High-throughput

0.513

High

1168230

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.513

High

1168242

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

0

High-throughput

0.513

High

1168248

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

1168254

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

0

High-throughput

0.513

High

1168257

LMA2L
VIP36-like protein

1

0

High-throughput

0.513

High

1168266

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.513

High

1168275

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

326105

TSN15
Tetraspanin-15

1

4

High-throughput

0.489

High

328347

S1PR4
Sphingosine 1-phosphate receptor 4

1

14

High-throughput

0.489

High

410571

CD1A
T-cell surface glycoprotein CD1a

1

1

High-throughput

0.489

High

579554

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

1

High-throughput

0.489

High

598745

S1PR1
Sphingosine 1-phosphate receptor 1

1

13

High-throughput

0.489

High

677599

NTR1
Neurotensin receptor type 1

1

6

High-throughput

0.489

High

699273

STX2
Syntaxin-2

1

1

High-throughput

0.489

High

723335

APJ
Apelin receptor

1

13

High-throughput

0.489

High

802338

5HT3A
5-hydroxytryptamine receptor 3A

1

1

High-throughput

0.489

High

813951

GPR12
G-protein coupled receptor 12

1

13

High-throughput

0.489

High

814578

P2RY1
P2Y purinoceptor 1

1

13

High-throughput

0.489

High

825065

PTH2R
Parathyroid hormone 2 receptor

1

8

High-throughput

0.489

High

849677

CCR6
C-C chemokine receptor type 6

1

11

High-throughput

0.489

High

880497

ATP5I
ATP synthase subunit e, mitochondrial

1

1

High-throughput

0.489

High

901797

STXB1
Syntaxin-binding protein 1

1

2

High-throughput

0.489

High

1030979

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

13

High-throughput

0.489

High

1079198

STXB2
Syntaxin-binding protein 2

1

2

High-throughput

0.489

High

1081929

PKN1
Serine/threonine-protein kinase N1

1

3

High-throughput

0.489

High

1119705

S39AC
Zinc transporter ZIP12

1

2

High-throughput

0.489

High

1161733

KLD10
Kelch domain-containing protein 10

1

1

High-throughput

0.489

High

1166210

VSTM1
V-set and transmembrane domain-containing protein 1

1

1

High-throughput

0.489

High

1168232

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.489

High

1168233

S22A9
Organic anion transporter 7

1

2

High-throughput

0.489

High

1168237

MACOI
Macoilin

1

1

High-throughput

0.489

High

1168256

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.489

High

1168263

LPAR2
Lysophosphatidic acid receptor 2

1

13

High-throughput

0.489

High

1168264

GPR35
G-protein coupled receptor 35

1

16

High-throughput

0.489

High

1168269

FZD4
Frizzled-4

1

2

High-throughput

0.489

High

1168270

FZD10
Frizzled-10

1

2

High-throughput

0.489

High

1168271

TNF18
Tumor necrosis factor ligand superfamily member 18

1

1

High-throughput

0.489

High

1168272

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

2

High-throughput

0.489

High

1168274

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.489

High

390307

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

1165698

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

205567

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

976346

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

8

High-throughput

0.437

High

1168229

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

236505

NEMF
Ribosome quality control complex subunit NEMF

1

1

High-throughput

0.407

High

1168249

TXD15
Thioredoxin domain-containing protein 15

3

0

High-throughput

0.347

High

966824

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.328

High

1168234

SUGP1
SURP and G-patch domain-containing protein 1

1

0

High-throughput

0.279

Low

1168238

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

1168239

SYT2
Synaptotagmin-2

1

0

High-throughput

0.279

Low

1168268

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.279

Low

553007

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

651508

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024