HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.49	0.50	0.498

Property	Details
Experiments	20080758
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 540
+	Hs
		903450 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		903374 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2C_HUMAN (57-528): 6.72e-09: 61: 10.42
+	Mm
		903669 WDR5_MOUSE (1-334): 2.77e-131: 379: 100.00		KMT2C_MOUSE (128-523): 8.47e-09: 60.6: 10.33
+	Hs
		209436 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		1102997 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1192155 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1103013 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		1281391 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PRR36_HUMAN (93-535): 5.51e-09: 61.4: 10.13
+	Hs
		1056932 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		1074805 TAF5_HUMAN (163-330): 6.22e-12: 68.6: 25.25		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58