HitPredict

Interactor 1: SMCA4 (P51532)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)
Gene: SMARCA4

Interactor 2: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	GO:0000776 - kinetochore GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1647 Hs			1 380
+	Hs
		903450 SMCA4_HUMAN (1-1647): 0: 1088: 100.00		FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30
+	Hs
		903453 SMCA4_HUMAN (1-1647): 0: 1088: 100.00		SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04
+	Hs
		903336 SMCA4_HUMAN (1-1647): 0: 1088: 100.00		RBBP4_HUMAN (216-378): 2.04e-19: 91.1: 13.59
+	Hs
		703356 SMCA1_HUMAN (639-1621): 0: 830: 29.20		NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75
+	Hs
		703359 SMCA1_HUMAN (639-1621): 0: 830: 29.20		FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30
+	Hs
		903141 SMCA2_HUMAN (40-1647): 0: 958: 72.59		RBBP4_HUMAN (216-378): 2.04e-19: 91.1: 13.59
+	Hs
		903169 SMCA2_HUMAN (40-1647): 0: 958: 72.59		RBBP7_HUMAN (216-378): 1.63e-18: 88.4: 14.13
+	Hs
		1088461 CHD3_HUMAN (270-1647): 0: 733: 21.04		NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75
+	Hs
		703360 SMCA1_HUMAN (639-1621): 0: 830: 29.20		SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04
+	Dm
		674032 BRM_DROME (211-1643): 0: 844: 53.24		EBI_DROME (246-376): 2.57e-17: 85.6: 12.25
+	Hs
		703300 SMCA1_HUMAN (639-1621): 0: 830: 29.20		RBBP4_HUMAN (216-378): 2.04e-19: 91.1: 13.59
+	Hs
		703326 SMCA1_HUMAN (639-1621): 0: 830: 29.20		RBBP7_HUMAN (216-378): 1.63e-18: 88.4: 14.13
+	Hs
		243613 SMCA5_HUMAN (594-1622): 0: 815: 27.27		RBBP4_HUMAN (216-378): 2.04e-19: 91.1: 13.59
+	Hs
		243650 SMCA5_HUMAN (594-1622): 0: 815: 27.27		RBBP7_HUMAN (216-378): 1.63e-18: 88.4: 14.13
+	Dm
		1173895 ISWI_DROME (620-1647): 0: 767: 27.93		CAF1_DROME (216-378): 1.52e-23: 102: 13.04
+	Ce
		836439 ISW1_CAEEL (616-1639): 0: 752: 27.09		LIN53_CAEEL (216-378): 1.68e-20: 94.1: 14.29
+	Hs
		1088500 CHD3_HUMAN (270-1647): 0: 733: 21.04		SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04
+	Hs
		209257 CHD3_HUMAN (270-1647): 0: 733: 21.04		PRP4_HUMAN (215-379): 7.78e-23: 101: 17.71
+	Hs
		1066276 CHD3_HUMAN (270-1647): 0: 733: 21.04		RBBP4_HUMAN (216-378): 2.04e-19: 91.1: 13.59
+	Hs
		1088371 CHD3_HUMAN (270-1647): 0: 733: 21.04		RBBP7_HUMAN (216-378): 1.63e-18: 88.4: 14.13