HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: RALY (Q9UKM9)
RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)
Gene: RALY

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 306
+	Mm
		904269 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		RALY_MOUSE (1-306): 9.64e-160: 449: 85.58
+	Hs
		432627 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		1072059 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		1356530 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		1283863 FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		1072124 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		432728 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		433017 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		71290 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		432970 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38