HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: DOCK9 (Q9BZ29)
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)
Gene: DOCK9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 2069
+	Hs
		909993 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DOCK9_HUMAN (1-2069): 0: 2505: 100.00
+	Hs
		909638 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DOC11_HUMAN (11-2068): 0: 2189: 58.38
+	Hs
		904658 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DOC11_HUMAN (11-2068): 0: 2189: 58.38
+	Hs
		982087 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DOC11_HUMAN (11-2068): 0: 2189: 58.38
+	Hs
		904844 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DOCK4_HUMAN (395-1225): 3.36e-176: 591: 14.85
+	Hs
		982263 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DOCK4_HUMAN (395-1225): 3.36e-176: 591: 14.85
+	Hs
		909527 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		904528 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		981984 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Mm
		56981 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		A2A9M5_MOUSE (11-205): 1.23e-48: 194: 25.35
+	Hs
		909920 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Hs
		904999 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Mm
		910246 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		Q3ZB59_MOUSE (169-364): 4.13e-44: 174: 22.93
+	Hs
		910172 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GAB2_HUMAN (170-500): 1.2e-43: 173: 18.38
+	Mm
		910297 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DOCK8_MOUSE (7-167): 1.06e-41: 171: 21.23
+	Hs
		905271 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		GAB2_HUMAN (170-500): 1.2e-43: 173: 18.38
+	Hs
		982379 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DOCK6_HUMAN (9-176): 1.25e-43: 177: 23.37
+	Hs
		910043 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PKHA1_HUMAN (149-366): 8.42e-36: 143: 18.83
+	Hs
		905130 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PKHA1_HUMAN (149-366): 8.42e-36: 143: 18.83
+	Hs
		108780 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		H0Y572_HUMAN (1329-1420): 1.39e-25: 105: 80.00