HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: TB22B (Q9NU19)
TBC1 domain family member 22B
Gene: TBC1D22B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 505
+	Hs
		910079 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TB22B_HUMAN (1-505): 9.73e-165: 477: 100.00
+	Mm
		910283 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		Q80VE5_MOUSE (1-505): 1.13e-164: 477: 98.81
+	Hs
		982543 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TB22B_HUMAN (1-505): 9.73e-165: 477: 100.00
+	Hs
		232659 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TBCD4_HUMAN (7-504): 2.2e-82: 280: 14.04
+	Mm
		910295 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		TBCD4_MOUSE (7-504): 7.52e-81: 276: 13.81
+	Hs
		232657 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TBCD4_HUMAN (7-504): 2.2e-82: 280: 14.04
+	Hs
		909751 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TBCD1_HUMAN (28-504): 5.48e-80: 272: 14.29
+	Hs
		904643 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TB10B_HUMAN (18-502): 2.38e-83: 276: 15.22
+	Hs
		904793 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TBCD1_HUMAN (28-504): 5.48e-80: 272: 14.29
+	Hs
		904782 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		Q7Z6H2_HUMAN (28-504): 9.09e-81: 271: 14.29
+	Hs
		232667 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TBCD4_HUMAN (7-504): 2.2e-82: 280: 14.04
+	Hs
		982075 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TB10B_HUMAN (18-502): 2.38e-83: 276: 15.22
+	Hs
		982218 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TBCD1_HUMAN (28-504): 5.48e-80: 272: 14.29
+	Hs
		904748 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TBCD9_HUMAN (51-494): 2.5e-74: 257: 13.26
+	Hs
		909872 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TBCD5_HUMAN (130-499): 5.89e-70: 240: 17.37
+	Hs
		904937 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TBCD5_HUMAN (130-499): 5.89e-70: 240: 17.37
+	Hs
		982349 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TBCD5_HUMAN (130-499): 5.89e-70: 240: 17.37
+	Hs
		232646 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		TBCD4_HUMAN (7-504): 2.2e-82: 280: 14.04
+	Hs
		683395 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		TB10B_HUMAN (18-502): 2.38e-83: 276: 15.22
+	Hs
		982072 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TBC25_HUMAN (187-441): 5.1e-46: 172: 20.15