HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PP4R4 (Q6NUP7)
Serine/threonine-protein phosphatase 4 regulatory subunit 4
Gene: PPP4R4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 873
+	Hs
		909683 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PP4R4_HUMAN (1-873): 0: 961: 100.00
+	Hs
		982145 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		PP4R4_HUMAN (1-873): 0: 961: 100.00
+	Hs
		683448 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		PP4R4_HUMAN (1-873): 0: 961: 100.00
+	Hs
		927171 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		PP4R4_HUMAN (1-873): 0: 961: 100.00
+	Hs
		647004 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		PP4R4_HUMAN (1-873): 0: 961: 100.00
+	Hs
		684123 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		PP4R4_HUMAN (1-873): 0: 961: 100.00
+	Hs
		268651 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SF3B1_HUMAN (39-691): 5.27e-80: 284: 12.16
+	Hs
		268647 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SF3B1_HUMAN (39-691): 5.27e-80: 284: 12.16
+	Hs
		268664 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		SF3B1_HUMAN (39-691): 5.27e-80: 284: 12.16
+	Hs
		672068 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		2AAA_HUMAN (396-680): 4.73e-09: 62.1: 11.93
+	Hs
		927364 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		GCN1_HUMAN (97-675): 1.79e-12: 73.7: 11.42
+	Hs
		672007 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		2AAA_HUMAN (396-680): 4.73e-09: 62.1: 11.93
+	Hs
		647159 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		GCN1_HUMAN (97-675): 1.79e-12: 73.7: 11.42
+	Mm
		926823 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		2AAA_MOUSE (396-680): 4.53e-09: 62.1: 11.93