Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: DNM3L (Q9UJW3)
DNA (cytosine-5)-methyltransferase 3-like
Gene: DNMT3L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 24952347
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000792 - heterochromatin
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0009791 - post-embryonic development
GO:0044027 - negative regulation of gene expression via chromosomal CpG island methylation
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 486
Hs

1 386
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025