HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 761
+	Mm
		910271 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		GIT1_MOUSE (1-761): 7.5e-170: 509: 96.62
+	Hs
		904553 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Hs
		982004 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Mm
		910346 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		GIT2_MOUSE (1-758): 4.51e-131: 407: 58.72
+	Hs
		60315 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		POTEF_HUMAN (31-683): 7.43e-63: 230: 13.13
+	Hs
		60314 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		POTEF_HUMAN (31-683): 7.43e-63: 230: 13.13
+	Hs
		60327 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		POTEF_HUMAN (31-683): 7.43e-63: 230: 13.13
+	Hs
		910161 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AGAP1_HUMAN (2-223): 4.13e-57: 211: 32.89
+	Hs
		905263 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AGAP1_HUMAN (2-223): 4.13e-57: 211: 32.89
+	Hs
		909925 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AGAP3_HUMAN (2-223): 6.5e-55: 205: 34.22
+	Hs
		904575 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ACAP1_HUMAN (2-297): 2.23e-56: 208: 23.77
+	Hs
		905003 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AGAP3_HUMAN (2-223): 6.5e-55: 205: 34.22
+	Hs
		909582 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ACAP2_HUMAN (2-331): 3.4e-53: 199: 18.50
+	Hs
		91532 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E7EUN2_HUMAN (2-223): 1.35e-54: 205: 32.89
+	Hs
		909866 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ARAP2_HUMAN (7-223): 6.18e-51: 195: 27.15
+	Hs
		904928 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ARAP2_HUMAN (7-223): 6.18e-51: 195: 27.15
+	Hs
		91533 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		E7EUN2_HUMAN (2-223): 1.35e-54: 205: 32.89
+	Hs
		909789 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANKH1_HUMAN (50-650): 2.73e-32: 137: 9.53
+	Hs
		904829 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ANKH1_HUMAN (50-650): 2.73e-32: 137: 9.53
+	Hs
		909455 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52